370878-49-2

Upstream product

• 72748-99-3 (R)-1-Amino-2-(methoxymethyl)pyrrolidine 
• 210173-60-7 3-(4′-tert-butyldimethylsilyloxy-3′-methoxyphenyl)propanal 
• 97-53-0 4-allylguaiacol 
• 214330-24-2 3-[3-methoxy-4-(tert-butyldimethylsiloxy)phenyl]-1-propene 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 370878-61-8 CHCH₂CH₂C₆H₃OCH₃OSiC₄H₉(CH₃)2CHOCH₂C₆H₅CHC₆H₃OCH₃OSiC₄H₉(CH₃)2 
• 370878-64-1 CHCH₂CH₂C₆H₃OCH₃OSiC₄H₉(CH₃)2CHOCHC₆H₃OCH₃OSiC₄H₉(CH₃)2Si(CH₃)3 
• 163634-08-0 (S)-(+)-imperanene 
• 370878-53-8 2-benzyloxymethyl-3-[4-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-phenyl]-propionaldehyde 
• 370878-52-7 2-benzyloxymethyl-3-[4-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-phenyl]-propionaldehyde 

Relevant academic research and scientific papers

Enantioselective synthesis of imperanene, a platelet aggregation inhibitor

matrix presented Both enantiomers of imperanene, a platelet aggregation inhibitor, have been synthesized in 82-90% ee. The key step of establishing the chiral center was achieved through stereoselective alkylation with benzyl chloromethyl ether using Enders' RAMP/SAMP chiral auxiliary method. The natural product was determined to be the (S)-enantiomer through comparison of optical rotation data.