37096-98-3

Upstream product

• 135-19-3 β-naphthol 
• 351-24-6 1-(3-fluorobenzylidene)-2-phenylhydrazine 
• 456-48-4 3-Fluorobenzaldehyde 

Relevant academic research and scientific papers

Functionalized mesoporous materials as efficient organocatalysts for the syntheses of xanthenes

Highly efficient and recyclable heterogeneous organocatalysts containing acidic functional groups such as CO2H and SO3H have been synthesized by post-synthesis modification of 2D-hexagonal mesoporous silica materials SBA-15 and MCM-4

Solvent-free synthesis of 14-aryl-14H-dibenzo[a-j]xanthenes using Fe3O4@Al2O3@SiO2@Fe2O3 as a green catalyst

We report, a novel, green, nano-sized particles as a sandwich nano-capsule multilayer catalyst (SNC@MC) [Fe3O4@Al2O3@SiO2@Fe2O3] for the efficacious one-pot synthesis of 14-aryl-

Br?nsted Acidic Ionic Liquid-Catalyzed Synthesis of 14-Aryl-14H-dibenzo[a,j]xanthenes with Controlled Microwave Heating under Solvent-Free Conditions

Abstract: 1-Methyl-3-sulfo-1H-imidazol-3-ium chloride([Msim]Cl) catalyzed the condensation of β-naphthol with aromatic aldehydesunder microwave irradiation. This method is efficient to synthesizedibenzoxanthene derivatives in excellent yields, and the cat

Fe+3-montmorillonite K10 as an Efficient Reusable Heterogeneous Catalyst for the Grind Mediated Synthesis of 14-aryl-14H-dibenzo [a,j]xanthenes

Background: Xanthenes are an important class of organic compounds and have also received significant attention due to their wide range of pharmacological activities such as antibacterial, antiviral, antiinflammatory activities, antagonists for the paralyzing action of zoxazolamine and efficiency in photodynamic therapy, a well-known method for controlling the localized tumors. Natural sources are also rich of xanthene compounds. Popularly known pigments, santalin have been isolated from plant species. Furthermore, these compounds can be emerged as pH-sensitive fluorescent materials for visualization of biomolecules, in laser technologies and as dyes. There are several reports in the literature for the synthesis of xanthenes such as alkylations of heteroatoms, cyclodehydrations, cyclocondensations between 2-hydroxyaromatic aldehydes and 2- tetralone, trapping of benzynes by phenols and intramolecular phenyl-carbonyl coupling reactions of benzaldehydes and acetophenones bearing tethered carbonyl chains in the presence of hexamethylphosphoramide and SmI2. Other methods for the synthesis of xanthenes include the reaction of formamide with β-naphthol, carbon monoxide, and 1- hydroxymethyl-naphthalen-2-ol. Methods: procedure a: A mixture of substituted benzaldehyde, 2-naphtol and Fe+3-montmorillonite K10 was mixed. After completion of the reaction, the product was solved in CHCl3 (3×10 mL) and insoluble catalyst was removed by filtration. The organic phase including the product and chloroform was evaporated under vacuum. The resulting crude material was purified by recrystallization from EtOH to afford pure products. procedure b: A mixture of substituted benzaldehyde, phenylhydrazine and Fe+3-montmorillonite K10 were added to a mortar and the mixture was pulverized with a pestle. After completion of the reaction, 2-naphtol was added to the consulting mixture and pulverized with a pestle. The organic phase including the product and chloroform was evaporated under vacuum. The resulting crude material was purified by recrystallization from EtOH to afford pure products. Results: As part of our going interest for the development of efficient and environmentally friendly procedures for the synthesis of heterocyclic and pharmaceutical compounds, we wish to report the first grind mediated synthesis of some derivatives of xanthenes using catalytic amount of Fe+3-montmotillonite. Conclusion: In conclusion, we have investigated the Fe+3-montmorillonite K10 under grinding as a mild and efficient catalyst for the synthesis of substituted 14-aryl-14H-dibenzo [a,j]xanthenes. The remarkable advantages offered by this method are: catalyst is inexpensive, non-toxic, easy handling and reusability, simple work-up procedure, short reaction time, high yields of product with better purity and green aspect by avoiding toxic catalyst and hazardous solvent.

1,4-Diazaniumbicyclo[2.2.2]octane diacetate: As an effective, new and reusable media for the synthesis of 14-aryl-14H-dibenzo[a,j]xanthenes

A general synthetic route to dibenzoxanthenes has been developed using 1,4-diazaniumbicyclo[2.2.2]octane diacetate as a new bis ionic liquid under thermal and solvent free condition. This method provides several advantages such as a simple work-up, environmental friendliness and shorter reaction time along with high yields. All of the synthesized compounds were characterized by infrared spectroscopy, 1H and 13C spectroscopy and elemental analyses.

Efficient one-pot synthesis of 14-aryl-14H-dibenzo[a,j]xanthene derivatives promoted by niobium pentachloride

A simple and efficient procedure for the synthesis of 14-aryl-14H-dibenzo[a,j]xanthene derivatives through one-pot condensation of 2-naphthol with aryl aldehydes in the presence of niobium pentachloride is described. The reactions were carried out using 2

Efficient one-pot synthesis of 14-aryl-14H-dibenzo[a,j]xanthene derivatives promoted by niobium pentachloride

A simple and efficient procedure for the synthesis of 14-aryl-14H-dibenzo[a,j ]xanthene derivatives through one-pot condensation of 2-naphthol with aryl aldehydes in the presence of niobium pentachloride is described. The reactions were carried out using

Phosphosulfonic acid, an efficient solid acid catalyst for the one-pot preparation of 14-aryl-14H-dibenzo[a,j]xanthenes and 1,8-dioxooctahydroxanthenes under solvent-free conditions

An expeditious procedure for the synthesis of 14-aryl-14H-dibenzo[ a,j]xanthenes and 1,8-dioxooctahydroxanthenes through a one-pot pseudo three component condensation of β-naphthol or dimedone with various aromatic aldehydes is described. This green proto

Microwave-assisted green synthesis of dibenzo[a,j]xanthenes using p-dodecylbenzenesulfonic acid as an efficient Bronsted acid catalyst under solvent-free conditions

The p-dodecylbenzenesulfonic acid (DBSA) has been successfully applied as an efficient acidic catalyst for the microwave-assisted synthesis of a series of 14-aryl- or alkyl-14H-dibenzo[a,j]xanthenes (3a-m) via a one-pot condensation-cyclization reaction o

An efficient synthesis of naphtha[1,2-e]oxazinone and 14-substituted-14H- dibenzo[a,j]xanthene derivatives promoted by zinc oxide nanoparticle under thermal and solvent-free conditions

A general synthetic route to the synthesis of 1,2-dihydro-1-arylnaphtho[1, 2-e][1,3]oxazine-3-one and 14-substituted-14H-dibenzo[a,j]xanthenes derivatives has been developed using ZnO-NPs under thermal and solvent-free conditions. The union of 2-naphthol,