371-49-3

Basic information

• Product Name: N-BUTYL FLUOROACETATE
• Synonyms: N-BUTYL FLUOROACETATE;BUTYL FLUOROACETATE;FLUOROACETIC ACID N-BUTYL ESTER;FLUOROACETIC ACID BUTYL ESTER;n-Butyl fluoroacetate 98%;n-Butylfluoroacetate98%;2-fluoroacetic acid butyl ester;butyl 2-fluoroacetate
• CAS NO: 371-49-3
• Molecular Formula: C₆H₁₁FO₂
• Molecular Weight: 134.15
• EINECS: 206-739-7
• Mol File: 371-49-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 154
• Flash Point: 43.7°C
• Appearance: /
• Density: 1.020
• Refractive Index: 1.3940 to 1.3970
• CAS DataBase Reference: N-BUTYL FLUOROACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: N-BUTYL FLUOROACETATE(371-49-3)
• EPA Substance Registry System: N-BUTYL FLUOROACETATE(371-49-3)

Safety Data

• Hazard Codes: T
• RIDADR: UN 2929 6.1/3/PG II
• HazardClass: TOXIC
• PackingGroup: II
• Hazardous Substances Data: 371-49-3(Hazardous Substances Data)

Usage

General Description

N-butyl fluoroacetate is an organic compound with the chemical formula C6H11FO2. It is a colorless, oily liquid that is sparingly soluble in water and easily soluble in organic solvents. N-butyl fluoroacetate is used in the production of pharmaceuticals and agrochemicals. It is also used as an intermediate in organic synthesis, particularly in the production of fluorine-containing compounds. It is considered to be toxic and is hazardous if ingested, inhaled, or absorbed through the skin. It is important to handle this compound with care and use appropriate safety precautions when working with it.

InChI:InChI=1/C6H11FO2/c1-2-3-4-9-6(8)5-7/h2-5H2,1H3

Upstream product

• 590-02-3 butyl chloroacetate 
• 503-20-8 fluoroacetonitrile 
• 71-36-3 butan-1-ol 
• 144-49-0 Fluoroacetic acid 
• 640-19-7 fluoroacetamide 
• 62-74-8 sodium fluoroacetate 

Downstream Products

• 392-67-6 2,4-difluoro-acetoacetic acid butyl ester 

Relevant articles and documents

A Gas Chromatography-Mass Spectrometry Method for the Detection and Quantitation of Monofluoroacetate in Plants Toxic to Livestock

Monofluoroacetate (MFA) is a potent toxin that occurs in over 50 plant species in Africa, Australia, and South America and is responsible for significant livestock deaths in these regions. A gas chromatography-mass spectrometry (GC-MS) method for the analysis of MFA in plants based on the derivatization of MFA with n-propanol in the presence of sulfuric acid to form propyl fluoroacetate was developed. This method compared favorably to a currently employed high-performance liquid chromatography-mass spectrometry (HPLC-MS) method for the analysis of MFA in plants. The GC-MS method was applied to the analysis of MFA in herbarium specimens of Fridericia elegans, Niedenzuella stannea, N. multiglandulosa, N. acutifolia, and Aenigmatanthera lasiandra. This is the first report of MFA being detected in F. elegans, N. multiglandulosa, N. acutifolia, and A. lasiandra, some of which have been reported to cause sudden death or that are toxic to livestock.