37100-45-1

Usage

Chemical class

o-carborane derivatives

Structure

Boron-containing molecule with two 4-methoxyphenyl groups attached to the o-carborane core

Unique properties

High thermal stability and resistance to oxidation and decomposition

Potential applications

a. Materials science
b. Pharmaceuticals
c. Nanotechnology

Boron-containing nature

Interest for potential use in boron neutron capture therapy for cancer treatment

Versatility

Wide range of applications due to its unique structure and properties

Upstream product

• 17702-41-9 nido-decaborane 
• 2132-62-9 4,4'-dimethoxydiphenylacetylene 
• 16872-09-6 1,2-dicarba-closo-dodecaborane⁽¹²⁾ 
• 696-62-8 para-iodoanisole 
• 3989-14-8 (4-methoxyphenylethynyl)trimethylsilane 

Downstream Products

• 51773-06-9 1,2-C₂B₁₀H₁₀-1,2-(C₆H₄OCOC₆H₅)2 
• 31177-92-1 1,2-C₂B₁₀H₁₀-1,2-(C₆H₄-4'-OH)2 

Relevant academic research and scientific papers

Preparation of dendritic carboranyl glycoconjugates as potential anticancer therapeutics

A series of carborane-appended glycoconjugates containing three and six glucose and galactose moieties have been synthesizedviaCu(i)-catalyzed azide-alkyne [3 + 2] click cycloaddition reaction. The carboranyl glycoconjugates containing three glucose and g

Metal-Free Oxidative B?N Coupling of nido-Carborane with N-Heterocycles

A general method for the oxidative substitution of nido-carborane (7,8-C2B9H12?) with N-heterocycles has been developed by using 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) as an oxidant. This metal-free B?N coupling strategy, in both inter- and intramolecular fashions, gave rise to a wide array of charge-compensated, boron-substituted nido-carboranes in high yields (up to 97 %) with excellent functional-group tolerance under mild reaction conditions. The reaction mechanism was investigated by density-functional theory (DFT) calculations. A successive single-electron transfer (SET), B?H hydrogen-atom transfer (HAT), and nucleophilic attack pathway is proposed. This method provides a new approach to nitrogen-containing carboranes with potential applications in medicine and materials.

Nickel-catalyzed cross-coupling reactions of o-carboranyl with aryl iodides: Facile synthesis of 1-aryl-o-carboranes and 1,2-diaryl-o-carboranes

A nickel-catalyzed arylation at the carbon center of o-carborane cages has been developed, thus leading to the preparation of a series of 1-aryl-o-carboranes and 1,2-diaryl-o-carboranes in high yields upon isolation. This method represents the first examp