37103-01-8Relevant academic research and scientific papers
2-Benzoyl-4-nitroanilides and their use as medicaments
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, (2008/06/13)
New derivatives of 2-benzoyl-4-nitro anilides, their preparation and their use as medicaments. The new chemical derivatives of the invention have the general formula STR1 in which R represents a linear or branched alkyl group, an alkenyl group, a cycloalkyl group or a benzyl group, R1 represents a hydrogen atom, an alkyl group or a hydroxy alkyl group, R2 represents a hydroxy-alkyl, alkenyl or alkynyl group, possibly substituted one or more times by an alkyl radical, or a cycloalkyl group having three to six carbon atoms; R1 and R2 may furthermore form, with the nitrogen atom to which they are attached, a nitrogen heterocycle containing possibly a second heteroatom selected from among oxygen and nitrogen; under the condition, however, that when R2 represents a hydroxy-alkyl group R1 may not be a hydrogen atom. Use as hypnotic agents for the treatment of insomnia.
