1859-76-3

Basic information

• Product Name: 2-(Methylamino)benzophenone
• Synonyms: 2-(Methylamino)benzophenone
• CAS NO: 1859-76-3
• Molecular Formula: C₁₄H₁₃NO
• Molecular Weight: 0
• Mol File: 1859-76-3.mol
• Article Data: 32

Chemical Properties

• Melting Point: 69°C
• Boiling Point: 350.95°C (rough estimate)
• Flash Point: 159.6°C
• Appearance: /
• Density: 1.0694 (rough estimate)
• Vapor Pressure: 2.96E-06mmHg at 25°C
• Refractive Index: 1.5780 (estimate)
• CAS DataBase Reference: 2-(Methylamino)benzophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Methylamino)benzophenone(1859-76-3)
• EPA Substance Registry System: 2-(Methylamino)benzophenone(1859-76-3)

Safety Data

• Hazardous Substances Data: 1859-76-3(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 100, p. 4842, 1978 DOI: 10.1021/ja00483a034

InChI:InChI=1/C14H13NO/c1-15-13-10-6-5-9-12(13)14(16)11-7-3-2-4-8-11/h2-10,15H,1H3

Upstream product

• 77-78-1 dimethyl sulfate 
• 2835-77-0 (2-aminophenyl)(phenyl)methanone 
• 29670-64-2 N-(2-benzoylphenyl)benzamide 
• 108-86-1 bromobenzene 
• 74-88-4 methyl iodide 
• 341521-27-5 (2-benzoylphenyl)carbamic acid tert-butyl ester 
• 74-89-5 methylamine 
• 93-89-0 benzoic acid ethyl ester 
• 1620-53-7 1-phenyl-2-pyridin-2-ylethanone 
• 69639-75-4 Dimethylammonium sulphite 
• 69639-76-5 ethylammonium sulphite 
• 16058-16-5 Dimethylammonium sulfite 
• 616-38-6 carbonic acid dimethyl ester 
• 34837-68-8 N-Methyl-N-phenylsulfonylanthranilsaeure 

Downstream Products

• 91409-65-3 [(2-Benzoyl-phenyl)-methyl-amino]-acetic acid ethyl ester 
• 154010-84-1 o-phenyl phenyl ketone 
• 260-94-6 acridine 
• 229-87-8 phenanthridine 
• 948-65-2 2-phenyl-indole 
• 133363-43-6 N-methyl-2-(1-phenylethenyl)benzenamine 
• 1610460-71-3 C₂₂H₁₉NO 
• 1610460-72-4 (1-methyl-3-phenyl-1H-indol-2-yl)(phenyl)methanol 
• 1610460-95-1 3-(cyclopropylmethyl)-1-methyl-3-phenylindolin-2-one 
• 1610460-94-0 1-methyl-3-phenyl-3-(thiophen-3-ylmethyl)indolin-2-one 
• 1610460-93-9 1-methyl-3-(naphthalen-1-ylmethyl)-3-phenylindolin-2-one 
• 1610460-91-7 1-methyl-3-phenyl-3-(4-(trifluoromethyl)benzyl)indolin-2-one 
• 1610460-90-6 3-(4-fluorobenzyl)-1-methyl-3-phenylindolin-2-one 
• 3336-00-3 3-benzyl-1-methyl-3-phenylindolin-2-one 

Relevant articles and documents

Tetrazoles: XLVI. 3H-1,3,4-benzo-and pyrido[6,7-b][1,3,4]triazepines from 5-aryltetrazoles. Synthesis and chemical properties

2,5-Disubstituted 3H-1,3,4-benzotriazepines were synthesized by heating of N-imidoyltetrazoles in toluene at 110°C. Alkylation of these compounds, as well as of 3H-pyrido[6,7-b][1,3,4]triazepines with alkyl halides in THF in the presence of potassium tert-butoxide gave the corresponding 1-alkyl derivatives in good yield and with high regioselectivity.

Palladacycle-Phosphine Catalyzed Methylation of Amines and Ketones Using Methanol

Methylation of amines and ketones with palladacycle precatalyst has been performed using methanol as an environmentally benign reagent. Various ketones and amines undergo methylation reaction to yield monomethylated amines or ketones in moderate to good isolated yields. Moreover, this protocol was tested for the chemoselective methylation of 4-aminobenzenesulfonamide. The scope of the reaction was further extended to the deuteromethylation of ketones.

Method for synthesizing ortho-amino aromatic ketone from aromatic carboxylic acid

Disclosed is a method for synthesizing ortho-amino aromatic ketone from aromatic carboxylic acid. The method comprises the steps that with 2-arylsulfonamido aromatic carboxylic acid shown in the description as a raw material and triphenylphosphine as a deoxidizer, under the illumination of blue light, in a 1,4-dioxane solution, under an argon atmosphere, in the presence of the dipotassium hydrogenphosphate, with [Ir(dF(CF3)ppy)2(dtbbpy)]PF6 as a photocatalyst, the ortho-amino aromatic ketone compound is obtained; the structure of the photocatalyst [Ir(dF(CF3)ppy)2(dtbbpy)]PF6 is shown in thedescription.