371123-28-3Relevant articles and documents
Copper(II) triflate: A versatile catalyst for the one-pot preparation of orthogonally protected glycosides
Tran, Anh-Tuan,Jones, Rachel A.,Pastor, Julien,Boisson, Julien,Smith, Nichola,Galan, M. Carmen
supporting information; experimental part, p. 2593 - 2598 (2011/12/04)
The development of general and expedient methodologies for the preparation of orthogonally protected glycoside building blocks is essential for the efficient synthesis of complex oligosaccharides. Herein, we describe a new approach that uses copper(II) triflate as a versatile catalyst for the one-pot preparation of orthogonal protected thio- and O-glycosides from the corresponding unprotected counterparts. The conditions are mild, easy to handle and applicable to two and three one-pot tandem transformations, which include arylidene acetalation, esterification, regioselective reductive acetal ring opening, glycosylation and silylation processes. Copyright