371252-41-4Relevant academic research and scientific papers
A convenient synthesis of antiviral acyclic C-nucleosides incorporating 1,3,4-thiadiazine nucleus as a nucleobase
Yadav,Singh,Dubey
, p. 674 - 677 (2007/10/03)
Adducts 4a-d obtained by nucleophilic addition of sulphenylated dimethyl sulphoxide derivatives 2a,b to glucose thiosemicarbazones 3a,b undergo intramolecular cyclisation, involving methanesulphinyl leaving group, with 90% H2SO4 and Pummerer rearrangement with glacial acetic acid to yield acyclic C-nucleosides, 2-arylamino-6-(5-aryl-1,3,4-thiadiazol-2-ylthio)-5-(D-glucopentyl)-4H,5,6- dihydro-1,3,4-thiadiazines 6a-d and 2-arylamino-6-(5-aryl-1,3,4-thiadiazol-2-ylthio)-5-(D-glucopentyl)-6- methylthio-4H,5,6-dihydro-1,3,4-thiadiazines 7a-d, respectively.
