37126-91-3

Usage

Uses

Used in Pharmaceutical Industry:
Murrangatin is used as an anti-tumor agent for its ability to inhibit the growth and progression of cancer cells. It targets multiple signaling pathways involved in tumor development, making it a promising candidate for cancer treatment.
Used in Medical Applications:
Murrangatin is used as an antibacterial agent, helping to combat bacterial infections and reduce the risk of disease transmission.
Used in Agriculture:
Murrangatin is used as an insecticidal agent, providing a natural alternative to synthetic pesticides for controlling pests and protecting crops.
Used in Pain Management:
Murrangatin is used as an analgesic, helping to alleviate pain and discomfort in various medical conditions.
Used in Anti-Inflammatory Applications:
Murrangatin is used as an anti-inflammatory agent, reducing inflammation and promoting healing in various medical conditions.

InChI:InChI=1/C15H16O5/c1-8(2)13(17)14(18)12-10(19-3)6-4-9-5-7-11(16)20-15(9)12/h4-7,13-14,17-18H,1H2,2-3H3/t13-,14+/m0/s1

Upstream product

• 67-56-1 methanol 
• 6545-99-9 Phebalosin 

Relevant academic research and scientific papers

COUMARINS OF MERRILLIA CALOXYLON

Key Word Index--Merrillia caloxylon; Rutaceae; isoprenylcoumarins; murrangatin; mexoticin; (-)-phebalosin; sibiricin; 7-methoxy-8-(1',2'-dihydroxy-3'-methylbutyl)coumarin; merillin.Abstract--From the roots of Merrillia caloxylon the five isoprenylcoumarins (-)-sibiricin, (-)-phebalosin, (-)-murrangatin, (-)-mexoticin and merillin were isolated.

Studies on Rutaceae: Part VI - Reacrtions and Rearrangements of Coumarins

Interesting reactions and rearrangements of isoprenoid systems have been observed in naturally occuring compounds like 6-(3',4'-epoxy-3'-methyl-γ-butyrolactonyl)-7-methoxycoumarin (micromelumin) (1), 7-methoxy-8-(1',2'-epoxy-3'-methylbut-3'-enyl)coumarin (phebalosin) (2), 7-methoxy-8-(2'-hydroxy-3'-methylbut-3'-enyl)coumarin (auraptenol) (3) and 7-methoxy-8-(3'-methylbut-2'-enyl)coumarin (osthol) (4).These reactions/rearrangements have led to the synthesis of coumarins already isolated from nature.Micromelumin (1) with pyridinium chloride affords the naturally occuring angelical (5), 6-(3'-methyl-3'-chloro-4'-hydroxy-γ-butyrolactonyl)- 7-methoxycoumarin (6b), 7-methoxycoumarinyl-6-tetronic acid derivative (7) and 6-(1'-carboxy-2'-methyl-3',4'-dihydroxybutenyl)-7-methoxycoumarin (8).Phebalosin (2) has been used for the hemisynthesis of the two naturally occuring diastereoisomeric coumarins minumicrolin (9) and murrangatin (10).Osthol (4) and auraptenol (3) have been used for the synthesis of the naturally occuring arnottinin (14)