37137-00-1

Basic information

• Product Name: (2-iodoethoxy)benzene
• CAS NO: 37137-00-1
• Molecular Formula: C₈H₉IO
• Molecular Weight: 248.0609
• Mol File: 37137-00-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 260°C at 760 mmHg
• Flash Point: 111°C
• Density: 1.667g/cm³
• Vapor Pressure: 0.0203mmHg at 25°C
• Refractive Index: 1.594
• CAS DataBase Reference: (2-iodoethoxy)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (2-iodoethoxy)benzene(37137-00-1)
• EPA Substance Registry System: (2-iodoethoxy)benzene(37137-00-1)

Safety Data

• Hazardous Substances Data: 37137-00-1(Hazardous Substances Data)

Usage

General Description

(2-iodoethoxy)benzene is a chemical compound that is also known as 1-phenoxy-2-iodoethane. It is a colorless liquid with a distinct aroma, and it is commonly used in the synthesis of various organic compounds. (2-iodoethoxy)benzene has a wide range of applications, including as an intermediate in the production of pharmaceuticals, agrochemicals, and dyes. It is also used in the manufacturing of polymers and as a solvent in various chemical processes. Additionally, (2-iodoethoxy)benzene has been studied for its potential use as a reagent in organic chemistry reactions, making it a versatile and valuable compound in industrial and scientific settings.

Upstream product

• 124004-35-9 C₁₄H₁₄O₄S 
• 141482-06-6 1-methanesulfonyloxy-2-(phenoxy)ethane 
• 589-10-6 phenoxyethyl bromide 
• 100716-80-1 4-chloro-benzenesulfonic acid-(2-phenoxy-ethyl ester) 

Downstream Products

• 334927-80-9 methyl 2-hydroxy-4-phenoxy-2-phenylbutanoate 
• 61040-70-8 4-chloro-N-(2-phenoxyethyl)aniline 
• 1579951-51-1 C₃₁H₃₂BrNO₄ 
• 1579951-52-2 C₂₂H₂₄O₄ 
• 1579951-56-6 C₃₄H₃₇BrN₄O₄ 
• 1579951-57-7 C₂₁H₂₁N₃O₃ 
• 1579951-58-8 C₂₁H₁₉N₃O₂ 
• 1579951-65-7 (4bR,7S,9aS,10aS)-7-((5-bromo-1-(tert-butyl)-1H-benzo[d][1,2,3]triazol-4-yl)methyl)-9a-methyl-7-(2-phenoxyethyl)-7,8,9,9a,10a,11-hexahydroindeno[1′,2′:4,5]-oxazolo[3,2-a]pyridin-6(4bH)-one 
• 1579951-67-9 C₂₅H₂₉N₃O₃ 
• 1398510-92-3 (S)-3-(tert-butyl)-9a-(2-phenoxyethyl)-8,9,9a,10-tetrahydrofluoreno[1,2-d][1,2,3]triazol-7(3H)-one 

Relevant articles and documents

CuCl2-Mediated Oxidative Intramolecular α-Arylation of Ketones with Phenolic Nucleophiles via Oxy-Allyl Cation Intermediates

α-Functionalization of ketones in an umpolung fashion can be achieved by nucleophilic addition to the oxy-allyl cation intermediate. However, applicable carbon nucleophiles are limited to ones with high nucleophilicity. Additionally, introduction of a lea

Enantioselective synthesis of a highly substituted tetrahydrofluorene derivative as a potent and selective estrogen receptor beta agonist

The development and execution of a practical asymmetric synthesis of the estrogen receptor beta selective agonist (8R,10aS)-6-(trifluoromethyl)-8,9,10, 11-tetrahydro-8,10a-methanocyclohepta[1,2]indeno[4,5-d][1,2,3]triazol-7(3H)-one is described. The optimized route features a key chiral auxiliary-mediated dialkylation approach to set the all-carbon quaternary center with exceptional stereocontrol. Overall, the chemistry has been used to prepare >30 kg of drug candidate in 21% overall yield through 13 longest linear steps and with >99% ee.

Substituted N-phenoxyethylanilines: preparation and acid-base properties evaluation by fluorescence spectrometry

Representative substituted N-phenoxyethylanilines were prepared starting on 1-bromo- or 1-iodo-2-phenoxyethanes and anilines in DMSO as the solvent, in mild reaction conditions. The acid dissociation constants of the N-aryl N-(2-aryloxyethyl) ammonium ion