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(2-iodoethoxy)benzene, also known as 1-phenoxy-2-iodoethane, is a colorless liquid chemical compound with a distinct aroma. It is commonly used in the synthesis of various organic compounds and has a wide range of applications in different industries.

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  • 37137-00-1 Structure
  • Basic information

    1. Product Name: (2-iodoethoxy)benzene
    2. Synonyms:
    3. CAS NO:37137-00-1
    4. Molecular Formula: C8H9IO
    5. Molecular Weight: 248.0609
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 37137-00-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 260°C at 760 mmHg
    3. Flash Point: 111°C
    4. Appearance: N/A
    5. Density: 1.667g/cm3
    6. Vapor Pressure: 0.0203mmHg at 25°C
    7. Refractive Index: 1.594
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: (2-iodoethoxy)benzene(CAS DataBase Reference)
    11. NIST Chemistry Reference: (2-iodoethoxy)benzene(37137-00-1)
    12. EPA Substance Registry System: (2-iodoethoxy)benzene(37137-00-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 37137-00-1(Hazardous Substances Data)

37137-00-1 Usage

Uses

Used in Pharmaceutical Industry:
(2-iodoethoxy)benzene is used as an intermediate in the production of pharmaceuticals for its ability to facilitate the synthesis of various medicinal compounds.
Used in Agrochemical Industry:
(2-iodoethoxy)benzene is used as an intermediate in the production of agrochemicals, contributing to the development of effective crop protection agents.
Used in Dye Industry:
(2-iodoethoxy)benzene is used as an intermediate in the production of dyes, enabling the creation of a diverse range of colorants for various applications.
Used in Polymer Industry:
(2-iodoethoxy)benzene is used in the manufacturing of polymers, playing a role in the development of new materials with specific properties.
Used in Chemical Processes:
(2-iodoethoxy)benzene is used as a solvent in various chemical processes, aiding in the efficient execution of reactions and the production of desired compounds.
Used in Organic Chemistry Research:
(2-iodoethoxy)benzene has been studied for its potential use as a reagent in organic chemistry reactions, making it a valuable tool for advancing scientific knowledge and the development of new chemical processes.

Check Digit Verification of cas no

The CAS Registry Mumber 37137-00-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,1,3 and 7 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 37137-00:
(7*3)+(6*7)+(5*1)+(4*3)+(3*7)+(2*0)+(1*0)=101
101 % 10 = 1
So 37137-00-1 is a valid CAS Registry Number.

37137-00-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-iodoethoxybenzene

1.2 Other means of identification

Product number -
Other names Benzene, (2-iodoethoxy)-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:37137-00-1 SDS

37137-00-1Relevant articles and documents

CuCl2-Mediated Oxidative Intramolecular α-Arylation of Ketones with Phenolic Nucleophiles via Oxy-Allyl Cation Intermediates

Aota, Yusuke,Kano, Taichi,Maruoka, Keiji,Mochimatsu, Takuto

supporting information, p. 3816 - 3819 (2020/10/19)

α-Functionalization of ketones in an umpolung fashion can be achieved by nucleophilic addition to the oxy-allyl cation intermediate. However, applicable carbon nucleophiles are limited to ones with high nucleophilicity. Additionally, introduction of a lea

Ni-Catalyzed Enantioselective Conjunctive Coupling with C(sp3) Electrophiles: A Radical-Ionic Mechanistic Dichotomy

Lovinger, Gabriel J.,Morken, James P.

supporting information, p. 17293 - 17296 (2017/12/15)

The catalytic enantioselective conjunctive coupling of C(sp3) electrophiles can be accomplished with Ni catalysis. The enantioselectivity of the reaction is dependent on reaction mechanism with many substrates able to engage in an asymmetric process with Pybox-Ni complexes, whereas other substrates provide racemic product mixtures. The link between substrate structure and selectivity is addressed.

Enantioselective synthesis of a highly substituted tetrahydrofluorene derivative as a potent and selective estrogen receptor beta agonist

Maddess, Matthew L.,Scott, Jeremy P.,Alorati, Anthony,Baxter, Carl,Bremeyer, Nadine,Brewer, Sarah,Campos, Kevin,Cleator, Ed,Dieguez-Vazquez, Alejandro,Gibb, Andrew,Gibson, Andrew,Howard, Melissa,Keen, Stephen,Klapars, Artis,Lee, Jaemoon,Li, Jing,Lynch, Joseph,Mullens, Peter,Wallace, Debra,Wilson, Robert

, p. 528 - 538 (2014/05/06)

The development and execution of a practical asymmetric synthesis of the estrogen receptor beta selective agonist (8R,10aS)-6-(trifluoromethyl)-8,9,10, 11-tetrahydro-8,10a-methanocyclohepta[1,2]indeno[4,5-d][1,2,3]triazol-7(3H)-one is described. The optimized route features a key chiral auxiliary-mediated dialkylation approach to set the all-carbon quaternary center with exceptional stereocontrol. Overall, the chemistry has been used to prepare >30 kg of drug candidate in 21% overall yield through 13 longest linear steps and with >99% ee.

Efficient procedures to prepare primary and secondary alkyl halides from alkanols via the corresponding sulfonates under mild conditions

Cahiez, Gerard,Gager, Olivier,Moyeux, Alban,Delacroix, Thomas

supporting information; experimental part, p. 1519 - 1528 (2012/07/03)

The study presented herein shows that sulfonate/halide exchange can be advantageously performed in THF to avoid several side reactions such as elimination and epimerization when the reaction is performed from a chiral alkyl sulfonate or a substrate having a C-H acidic chiral center. The main limitation of this procedure was found to be the conversion of secondary alkyl sulfonates to alkyl chlorides. In this case, the addition of a catalytic amount of manganese chloride clearly accelerates the rate and the efficiency of the reaction. Copyright

Substituted N-phenoxyethylanilines: preparation and acid-base properties evaluation by fluorescence spectrometry

Autino, Juan C.,Bruzzone, Liliana,Romanelli, Gustavo P.,Jios, Jorge L.,Ancinas, Horacio A.

, p. 292 - 294 (2007/10/03)

Representative substituted N-phenoxyethylanilines were prepared starting on 1-bromo- or 1-iodo-2-phenoxyethanes and anilines in DMSO as the solvent, in mild reaction conditions. The acid dissociation constants of the N-aryl N-(2-aryloxyethyl) ammonium ion

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