3715-64-8 Usage
Uses
Used in Pharmaceutical Industry:
[(2S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen phosphate is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows it to form hydrogen bonds and other interactions with biological targets, making it a promising candidate for the development of new drugs.
Used in Biochemical Research:
In the field of biochemical research, [(2S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen phosphate can be employed as a model compound for studying enzyme-substrate interactions and the mechanisms of various biological processes. Its ability to form hydrogen bonds with enzymes, such as human thymidylate kinase, can provide valuable insights into the design of novel compounds with potential therapeutic applications.
Used in Drug Design and Development:
[(2S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen phosphate's unique structure and ability to form hydrogen bonds make it a valuable tool in the field of drug design and development. Structure-based design studies can utilize [(2S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen phosphate as a starting point for the development of new drugs targeting specific biological pathways or enzymes. Its potential as a model for novel compounds can lead to the discovery of new therapeutic agents with improved efficacy and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 3715-64-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,7,1 and 5 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 3715-64:
(6*3)+(5*7)+(4*1)+(3*5)+(2*6)+(1*4)=88
88 % 10 = 8
So 3715-64-8 is a valid CAS Registry Number.
3715-64-8Relevant academic research and scientific papers
2-Nucleos-5'-O-yl-4H-1,3,2-benzodioxaphosphinin-2-oxide - ein neues Konzept fuer lipophile, potentielle Prodrugs biologisch aktiver Nucleosidmonophosphate
Meier, Chris
, p. 77 - 79 (2007/10/03)
Keywords: AIDS; Chemotherapie; Phosphotriester-Prodrugs; Prodrugs; Thymidinderivate
Analogs of pyrimidine nucleosides. 16. Racemic 2′,3′-dideoxynucleosides and their derivatives
Kaulinya,Liepin'sh,Lidak,Zhuk
, p. 85 - 93 (2007/10/02)
The chlorination of 2-halomethyltetrahydrofurans and acyl derivatives of tetrahydrofuryl alcohol wasstudied; mixtures of 2,5- and 2,2-disubstituted tetrahydrofurans are formed as a result of the reaction. 2,4-Bis(trimethylsilyl) derivatives of uracil, 5-substituted uracils, and cytosine are alkylated by the resulting mixtures of α-chloro ethers without separation, and mixtures of cis and transisomers of 1-(5-substituted-2-tetrahydrofuryl) and 1-(2-substituted-2-tetrahydrofuryl) derivatives of uracil, 5-substituted uracils, and cytosine are obtained. The reaction products were identified onthe basis of their PMR spectra.
