371785-35-2

Upstream product

• 40137-29-9 2-methyl-4-chlorobenzaldehyde 
• 107-21-1 ethylene glycol 

Downstream Products

• 371785-39-6 2-methyl-4-trimethylsilylbenzaldehyde 
• 944913-41-1 (E)-N-benzyl-1-(o-tolyl)methanimine 
• 371785-37-4 2-methyl-4-trimethylsilylbenzaldehyde ethylene acetal 

Relevant academic research and scientific papers

Diastereoselective synthesis of trans-N-benzyl-2-(2-methylphenyl)-6-phenyl-4-piperidone

Diastereoselective synthesis of trans-N-benzyl-2-(2-methylphenyl)-6-phenyl-4-piperidone (6a) was performed by cycloaddition of the aldimine (1c) with 2-silyloxy-l,3-butadiene in the presence of trimethylsilyl triflate. The use of the p-trimethylsilyl substituent of the aromatic ring of the aldimine gave high diastereoselectivity of the product.