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1-(Trifluoromethyl)cyclopropanemethanol is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 371917-17-8 Structure
  • Basic information

    1. Product Name: 1-(Trifluoromethyl)cyclopropanemethanol
    2. Synonyms: 1-(Trifluoromethyl)cyclopropanemethanol;(1-TrifluoroMethyl-cyclopropyl)-Methanol
    3. CAS NO:371917-17-8
    4. Molecular Formula: C5H7F3O
    5. Molecular Weight: 140
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 371917-17-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 95℃
    3. Flash Point: 51℃
    4. Appearance: /
    5. Density: 1.356
    6. Refractive Index: N/A
    7. Storage Temp.: Sealed in dry,Store in freezer, under -20°C
    8. Solubility: N/A
    9. PKA: 15.10±0.10(Predicted)
    10. CAS DataBase Reference: 1-(Trifluoromethyl)cyclopropanemethanol(CAS DataBase Reference)
    11. NIST Chemistry Reference: 1-(Trifluoromethyl)cyclopropanemethanol(371917-17-8)
    12. EPA Substance Registry System: 1-(Trifluoromethyl)cyclopropanemethanol(371917-17-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 371917-17-8(Hazardous Substances Data)

371917-17-8 Usage

Uses

[1-(trifluoromethyl)cyclopropyl]methanol is a useful research chemical.

Check Digit Verification of cas no

The CAS Registry Mumber 371917-17-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,1,9,1 and 7 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 371917-17:
(8*3)+(7*7)+(6*1)+(5*9)+(4*1)+(3*7)+(2*1)+(1*7)=158
158 % 10 = 8
So 371917-17-8 is a valid CAS Registry Number.

371917-17-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name [1-(trifluoromethyl)cyclopropyl]methanol

1.2 Other means of identification

Product number -
Other names 1-Hydroxymethyl-1-(trifluoromethyl)cyclopropane

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:371917-17-8 SDS

371917-17-8Downstream Products

371917-17-8Relevant articles and documents

SUBSTITUTED IMIDAZOLE CARBOXAMIDES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS

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Paragraph 00245; 00255; 00259, (2021/04/01)

The invention provides substituted imidazole carboxamides and related compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat a medical disorder, e.g., cancer, lysosomal storage disorder, neurodegenerative disorder, inflammatory disorder, in a patient.

REV-ERB AGONISTS FOR THE TREATMENT OF TH17-MEDIATED INFLAMMATORY DISORDERS

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Paragraph 001794-001796, (2022/01/05)

The present disclosure provides compounds of Formula IA and Formula IB and their pharmaceutical compositions as selective agonists of REV-ERB-α: where R1, R2, R3, R4, R5, RX1, RX2, nA, nB, X, Y, and Z are described herein. The compounds are useful in various methods and uses, such as in the treatment of diseases including hyperglycemia, dyslipidemia, atherosclerosis, and autoimmune and inflammatory disorders or diseases, and as cancer therapeutics, such as for the treatment of glioblastoma, hepatocellular carcinoma, and colorectal cancer, and for immune-oncology purposes.

5-MEMBERED HETEROARYLAMINOSULFONAMIDES FOR TREATING CONDITIONS MEDIATED BY DEFICIENT CFTR ACTIVITY

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Page/Page column 385, (2021/05/21)

The invention relates to heteroaryl compounds, pharmaceutically acceptable salts thereof, and pharmaceutical preparations thereof. Also described herein are compositions and the use of such compounds in methods of treating diseases and conditions mediated by deficient CFTR activity, in particular cystic fibrosis.

DIAZANAPHTHALEN-3-YL CARBOXAMIDES AND PREPARATION AND USE THEREOF

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Paragraph 0924-0925, (2019/05/15)

Diazanaphthalene compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of a diazanaphthalene compound or analogs thereof, in the treatment of disorders characterized by the activa

5-(PYRIDIN-3-YL)OXAZOLE ALLOSTERIC MODULATORS OF M4 MUSCARINIC ACETYLCHOLINE RECEPTOR

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Page/Page column 34, (2019/01/16)

Provided are 5-(pyridin-3-yl) oxazole compounds, the compositions comprising these compounds and the uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.

MODULATOR OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR, PHARMACEUTICAL COMPOSITIONS, METHODS OF TREATMENT, AND PROCESS FOR MAKING THE MODULATOR

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Paragraph 00648; 00649, (2018/04/17)

Compounds of Formula (I), pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed.

MODULATOR OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR, PHARMACEUTICAL COMPOSITIONS, METHODS OF TREATMENT, AND PROCESS FOR MAKING THE MODULATOR

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Page/Page column 161; 162, (2018/06/30)

Compounds of Formula (I) pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed. Also disclosed are solid state forms of Compound 1 and salts and solvates thereof.

ISOQUINOLIN-3-YL CARBOXAMIDES AND PREPARATION AND USE THEREOF

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Paragraph 0825; 0826, (2017/11/16)

Isoquinoline compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of an isoquinoline compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease, lung disease, inflammation, auto-immune diseases and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as neurological conditions/disorders/diseases linked to overexpression of DYRK1A.

Substituted Oxopyridine Derivatives and Use Thereof in the Treatment of Cardiovascular Disorders

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Paragraph 1690-1692, (2016/05/02)

The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.

1-(HET)ARYLSULFONYL-(PYRROLIDINE OR PIPERIDINE)-2-CARBOXAMIDE DERIVATIVES AND THEIR USE AS TRPA1 ANTAGONISTS

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Paragraph 01039; 01040; 01041, (2016/09/22)

The invention is concerned with the compounds of formula I and salts thereof and other compounds of formulas II-IX as disclosed herein. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formulas I-IX as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain or asthma.

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