371978-09-5

Basic information

• Product Name: (1R,2R,3S,4R)-1,2-di-O-isopropylidene-4,5-epoxy-3-methyl-1-phenyl-pentan-1,2-diol
• Synonyms: (1R,2R,3S,4R)-1,2-di-O-isopropylidene-4,5-epoxy-3-methyl-1-phenyl-pentan-1,2-diol
• CAS NO: 371978-09-5
• Molecular Weight: 248.322
• Mol File: 371978-09-5.mol

Chemical Properties

• CAS DataBase Reference: (1R,2R,3S,4R)-1,2-di-O-isopropylidene-4,5-epoxy-3-methyl-1-phenyl-pentan-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R,3S,4R)-1,2-di-O-isopropylidene-4,5-epoxy-3-methyl-1-phenyl-pentan-1,2-diol(371978-09-5)
• EPA Substance Registry System: (1R,2R,3S,4R)-1,2-di-O-isopropylidene-4,5-epoxy-3-methyl-1-phenyl-pentan-1,2-diol(371978-09-5)

Safety Data

• Hazardous Substances Data: 371978-09-5(Hazardous Substances Data)

Upstream product

• 371978-07-3 {(2S,3R)-3-[(4R,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]oxiran-2-yl}methanol 
• 371978-06-2 (E)-3-[(4R,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]prop-2-en-1-ol 
• 371978-05-1 (1R,2R,3E)-1-phenyl-pent-3-en-1,2,5-triol 
• 211614-43-6 methyl (R)-(methoxymethoxy)(phenyl)ethanoate 
• 211614-44-7 (1R,2R)-5-(tert-butyldiphenylsilyloxy)-1-methoxymethoxy-1-phenyl-pent-3-yn-2-ol 
• 211614-45-8 (1R,2R,3E)-5-(tert-butyldiphenylsilyloxy)-1-methoxymethoxy-1-phenyl-pent-3-ene-2-ol 
• 371978-08-4 (1R,2R,3S,4R)-1,2-di-O-isopropylidene-3-methyl-1-phenyl-pentan-1,2,4,5-tetrol 

Downstream Products

• 371978-11-9 (3S,4R)-3-(tert-Butyl-dimethyl-silanyloxy)-4-((4R,5R)-2,2-dimethyl-5-phenyl-[1,3]dioxolan-4-yl)-pentanenitrile 
• 371978-12-0 (3S,4S,5R,6R)-3-tert-butyldimethylsilyloxy-5,6-di-O-isopropylidenedioxy-4-methyl-6-phenyl-hexanal 
• 371978-10-8 (3S,4S)-4-((4R,5R)-2,2-Dimethyl-5-phenyl-[1,3]dioxolan-4-yl)-3-hydroxy-pentanenitrile 

Relevant articles and documents

Diastereocontrolled synthesis of unit A of cryptophycin

Cryptophycin fragment A was prepared in 11 steps from protected methyl (R)-mandelate 4. A diastereoselective addition of magnesium acetylide to methyl mandelate and a Sharpless epoxidation followed by regioselective opening of the resulting epoxide allowe