372-52-1

Basic information

• Product Name: epsilon-Aminocaproic acid hexyl ester
• Synonyms: epsilon-Aminocaproic acid hexyl ester
• CAS NO: 372-52-1
• Molecular Formula: C12H25 N O2
• Molecular Weight: 0
• Mol File: 372-52-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 287.3°Cat760mmHg
• Flash Point: 145.2°C
• Appearance: /
• Density: 0.921g/cm³
• Vapor Pressure: 0.00251mmHg at 25°C
• Refractive Index: 1.451
• CAS DataBase Reference: epsilon-Aminocaproic acid hexyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: epsilon-Aminocaproic acid hexyl ester(372-52-1)
• EPA Substance Registry System: epsilon-Aminocaproic acid hexyl ester(372-52-1)

Safety Data

• Hazardous Substances Data: 372-52-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H25NO2/c1-2-3-4-8-11-15-12(14)9-6-5-7-10-13/h2-11,13H2,1H3

Upstream product

• 4321-58-8 6-aminohexanoic acid hydrochloride 
• 40772-92-7 ε-aminocaproyl chloride hydrochloride 
• 111-27-3 hexan-1-ol 

Downstream Products

• 244055-05-8 6-[N-(4-nitrobenzyl)-N-propyl]-amino caproic acid 

Relevant articles and documents

Esters of ω-amino acids as flexible penetration enhancers

Series of esters of 6-aminohexanoic acid, 7-aminoheptanoic acid, and 8-aminooctanoic acid were synthesized as candidates for novel skin penetration enhancers. The permeation of theophylline expressed in the form of the enhancement factor (EF) was studied with human cadaver skin by a diffusion cell technique in the presence of the esters 1-17 in the water vehicle. The permeation in the presence of the 6-aminohexanoates 1-5 was also studied in the olive oil vehicle. Of the compounds tested, the most satisfactory enhancement in the water vehicle and oil vehicle were observed with octyl 6-aminohexanoate (EF = 45.5) and decyl 6-aminohexanoate (EF = 19.5), respectively.