372-80-5

Basic information

• Product Name: hexanoyl fluoride
• Synonyms: hexanoyl fluoride;Hexanoic acid fluoride
• CAS NO: 372-80-5
• Molecular Formula: C₆H₁₁FO
• Molecular Weight: 118.1493432
• EINECS: 206-760-1
• Mol File: 372-80-5.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 132.4°Cat760mmHg
• Flash Point: 44.2°C
• Appearance: /
• Density: 0.907g/cm³
• Vapor Pressure: 8.9mmHg at 25°C
• Refractive Index: 1.378
• CAS DataBase Reference: hexanoyl fluoride(CAS DataBase Reference)
• NIST Chemistry Reference: hexanoyl fluoride(372-80-5)
• EPA Substance Registry System: hexanoyl fluoride(372-80-5)

Safety Data

• Hazardous Substances Data: 372-80-5(Hazardous Substances Data)

Usage

General Description

Hexanoyl fluoride, also known as caproyl fluoride, is a chemical compound that consists of six carbon atoms and a fluorine atom. It is used in the synthesis of pharmaceuticals and agrochemicals, as well as in the manufacturing of various organic compounds. Hexanoyl fluoride is a colorless liquid with a sharp, pungent odor, and it is highly reactive due to the presence of the fluoride group. It is flammable and may release toxic fumes when heated, so it should be handled and stored with caution. Hexanoyl fluoride is primarily used as an intermediate in the production of other compounds and is not commonly found in consumer products.

InChI:InChI=1/C6H11FO/c1-2-3-4-5-6(7)8/h2-5H2,1H3

Upstream product

• 142-62-1 hexanoic acid 
• 455-32-3 benzoyl fluoride 
• 61103-84-2 benzyl hexyl ether 
• 112-58-3 dihexyl ether 
• 66-25-1 hexanal 
• 111-27-3 hexan-1-ol 
• 2051-49-2 n-hexanoic anhydride 
• 142-61-0 Hexanoyl chloride 

Downstream Products

• 6283-98-3 N-benzylhexanamide 
• 355-38-4 perfluorohexanoyl fluoride 
• 6938-45-0 benzyl hexanoate 

Relevant articles and documents

Homogeneous catalytic hydrogenation of perfluoro methyl esters

The first example of perfluoroalkyl methyl ester RfC(O)OMe (Rf = C3F7, C5F11) reduction by homogeneous catalytic hydrogenation with the ruthenium catalyst Ru-MACHO is herein reported. The hydrogenation process leads to the corresponding perfluorinated alcohols thus replacing sodium borohydride that has so far represented the state of art in perfluoro ester reduction.

Reactions of caesium fluoroxysulphate with organic molecules part 25 1. Reactions with ethers

The reactions of caesium fluoroxysulphate in MeCN suspension at room temperature with di-benzyl, di-alkyl or benzyl-alkyl ethers resulted in oxidative cleavage of the ethers forming pairs of corresponding aldehydes and alcohols, which could be further transformed into acid fluorides under the reaction conditions used. Di-benzyl ether was thus transformed to a mixture of benzyl alcohol, benzaldehyde and benzoyl fluoride as the main products and benzyl benzoate as the a minor one, while di-n-hexyl ether resulted in a mixture of n-hexanol, hexanal, hexanoyl fluoride and hexyl hexanoate. The reaction of benzyl hexyl ether resulted in a mixture of benzaldehyde, benzoyl fluoride and hexanol as the main, and benzyl alcohol, hexanal, hexanoyl fluoride and hexyl benzoate as the minor products. A reaction mechanism including radical intermediates was proposed.