372109-60-9Relevant academic research and scientific papers
Enantiopure 2,3-dihydro-4-pyridones as synthetic intermediates: Asymmetric synthesis of 1-deoxynojirimycin
Comins, Daniel L,Fulp, Alan B
, p. 6839 - 6841 (2007/10/03)
An asymmetric synthesis of 1-deoxynojirimycin (2) mediated by a chiral auxiliary is reported. The dihydropyridone 4 was converted to diol 11 in three steps by acetoxylation, hydrolysis, and stereoselective reduction. Dihydroxylation of 11 followed by catalytic reduction afforded 2.
