372157-30-7Relevant academic research and scientific papers
Synthesis of pyrazol-quinazolinones and 2,3-dihydroquinazolin-4(1H)-ones using CoAl2O4 nanoparticles as heterogeneous catalyst
Ahmadian, Fatemeh,Barmak, Alireza,Ghaderi, Esmali,Bavadi, Masoumeh,Raanaei, Hossein,Niknam, Khodabakhsh
, p. 2647 - 2658 (2019/07/17)
Abstract: The preparation and characterization of cobalt aluminate (CoAl2O4) magnetic nanoparticles and its application as a catalyst for the synthesis of a novel class of pyrazol-quinazolinones and 2,3-dihydroquinazolin-4(1H)-ones is described. The structure of the catalyst was studied by Fourier transform infrared spectroscopy, transmission electron microscopy, X-ray diffraction, and vibrating sample magnetometer analysis. The resulting cobalt aluminate (CoAl2O4) was an efficient catalyst and affords the desired products in good to excellent yields. Moreover, the catalyst could be easily recovered by magnetic separation and recycled for four times without significant loss of its catalytic activity. Graphic abstract: 2,3-Dihydroquinazolin-4(1H)-ones and a novel class of pyrazol-quinazolinones were synthesized through one-pot condensation reaction of isatoic anhydride, aromatic aldehydes, and amines using CoAl2O4 as nanoparticle heterogeneous catalyst in refluxing ethanol.[Figure not available: see fulltext.].
Access to enhanced catalytic core-shell CuO-Pd nanoparticles for the organic transformations
Mishra, Kanchan,Basavegowda, Nagaraj,Lee, Yong Rok
, p. 27974 - 27982 (2016/03/30)
This paper describes the biosynthesis of core-shell CuO-Pd nanoparticles with the aid of a Cyperus rotundus rhizome extract. The crystallinity, surface chemistry, morphology and thermal properties of the synthesized nanoparticles were characterized by X-ray diffraction, X-ray photoelectron spectroscopy, transmission electron microscopy, and thermogravimetric analysis. The nanoparticles with Pd covered by a CuO enriched shell showed enhanced catalytic performance for organic transformations to synthesize 2,3-dihydroquinazolin-4(1H)-ones, spirooxindoles, and chromenylpyrimidin-2,4-diones in excellent yield. Moreover, the nanocatalyst can be recycled effectively for five consecutive reactions without significant loss of catalytic activity.
Ethylenediamine diacetate-catalyzed three-component reaction for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones and their spirooxindole derivatives
Narasimhulu, Manchala,Lee, Yong Rok
experimental part, p. 9627 - 9634 (2011/12/14)
Ethylenediamine diacetate (EDDA)-catalyzed one-pot syntheses of biologically interesting 2,3-dihydroquinazolin-4(1H)-ones and their spirooxindole derivatives from isatoic anhydride, amines, and benzaldehydes or isatins via a three-component condensation in aqueous media have been described. This method is of great value because of high yields and ease of handling.
