372187-50-3

Upstream product

• 95715-87-0 (R)-3-tert-butoxycarbonyl-4-formyl-2,2-dimethyloxazolidine 
• 146356-00-5 N-methoxycarbonyl (S)-pyroglutamic acid benzylester 
• 372187-39-8 (2S)-benzyl-5-methoxy-1-methoxycarbonyl-2-pyrrolidinecarboxylate 
• 94885-52-6 benzyl (L)-pyroglutamate 
• 372187-25-2 (2R,5R)-5-allyl-2-[(1S,2R)-2-tert-butoxycarbonylamino-3-(tert-butyldimethylsilanyl-oxy)-1-hydroxypropyl]pyrrolidine-1,2-dicarboxylic acid, 2-benzyl ester, 1-methyl ester 
• 372187-24-1 (2R,5R)-5-allyl-2-[(1R,2R)-2-tert-butoxycarbonylamino-3-(tert-butyldimethylsilanyloxy)-1-hydroxypropyl]pyrrolidine-1,2-dicarboxylic acid, 2-benzyl ester, 1-methyl ester 
• 372187-46-7 5-allyl-2-[2-tert-butoxycarbonylamino-3-(tert-butyl-dimethyl-silanyloxy)-propionyl]-pyrrolidine-1,2-dicarboxylic acid 2-benzyl ester 1-methyl ester 
• 372187-43-4 (2R,5R)-5-Allyl-2-[(R)-((R)-3-tert-butoxycarbonyl-2,2-dimethyl-oxazolidin-4-yl)-hydroxy-methyl]-pyrrolidine-1,2-dicarboxylic acid 2-benzyl ester 1-methyl ester 
• 372187-41-2 (2S,5R)-1-methoxycarbonyl-2-benzoxycarbonyl-5-(2-propenyl)-pyrrolidine 
• 100-51-6 benzyl alcohol 
• 98-79-3 L-Pyroglutamic acid 

Downstream Products

• 372187-29-6 (2R,5R)-2-[(1S,2R)-1,3-diacetoxy-2-tert-butoxycarbonylaminopropyl]-5-[(R)-3-(tert-butyldiphenylsilanyloxy)-2-hydroxypropyl]pyrrolidine-1,2-dicarboxylic acid, 2-benzyl ester, 1-methyl ester 
• 433232-07-6 kaitocephalin 
• 372187-31-0 (2R,5R)-2-[(1S,2R)-1,3-diacetoxy-2-tert-butoxycarbonylaminopropyl]-5-[(R)-3-hydroxy-2-methanesulfonyloxypropyl]pyrrolidine-1,2-dicarboxylic acid, 2-benzyl ester, 1-methyl ester 
• 372187-37-6 (1S,5R,7aR)-1-(S-tert-butoxycarbonylamino-carbonylmethyl)-5-[S-2-(3,5-dichloro-4-benzoxybenzoylamino)-2-methoxycarbonylethyl]-3-oxo-dihydropyrrolo[1,2-c]oxazole-7a-carboxylic acid, methyl ester 
• 372187-27-4 (2R,5R)-5-allyl-2-[(1S,2R)-1,3-diacetoxy-2-tert-butoxycarbonylaminopropyl]-pyrrolidine-1,2-dicarboxylic acid, 2-benzyl ester, 1-methyl ester 

Relevant academic research and scientific papers

Reinvestigation on total synthesis of kaitocephalin and its isomers

Aldol reaction of 2,5-disubstituted pyrrolidine 3b with (R)-Garner aldehyde followed by Sharpless asymmetric dihydroxylation and other four reactions afforded mesylate 8a, which was introduced by an amide group via three ordinary transformations to provid