372187-92-3

Basic information

• Product Name: 2-(5,6-difluoro-1H-benzoimidazol-2-ylsulfanyl)-1-o-tolyl-ethanone
• Synonyms: 2-(5,6-difluoro-1H-benzoimidazol-2-ylsulfanyl)-1-o-tolyl-ethanone
• CAS NO: 372187-92-3
• Molecular Weight: 318.347
• Mol File: 372187-92-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(5,6-difluoro-1H-benzoimidazol-2-ylsulfanyl)-1-o-tolyl-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(5,6-difluoro-1H-benzoimidazol-2-ylsulfanyl)-1-o-tolyl-ethanone(372187-92-3)
• EPA Substance Registry System: 2-(5,6-difluoro-1H-benzoimidazol-2-ylsulfanyl)-1-o-tolyl-ethanone(372187-92-3)

Safety Data

• Hazardous Substances Data: 372187-92-3(Hazardous Substances Data)

Upstream product

• 123470-47-3 5,6-difluoro-1H-benzo[d]imidazole-2-thiol 
• 76179-40-3 2-amino-4,5-difluoroaniline 
• 78056-39-0 4,5-difluoro-2-nitroaniline 

Downstream Products

• 372187-97-8 2-(1-acetyl-5,6-difluoro-1H-benzoimidazol-2-ylsulfanyl)-1-o-tolyl-ethanone 

Relevant articles and documents

Fluoro-containing heterocycles. IV. Synthesis of benzimidazole derivatives

2-Mercapto-5,6-difluorobenzimidazole reacts with aliphatic and alicyclic ketones in acetic acid in the presence of catalytic amount of sulfuric acid to afford fluorinated derivatives of 2,3-disubstituted benz[4,5]imidazo[2,1-b][1,3]thiazoles. Reaction with aromatic α-haloketones occurs in another way: to furnish 2-phenylacylthio-5,6-difluorobenzimidazoles that in the system acetic anhydride - pyridine undergo cyclization into the corresponding fluorinated derivatives of benz[4,5]imidazo[2,1-b][1,3]thiazoles.