3723-71-5

Upstream product

• 5470-18-8 2-Chloro-3-nitropyridine 
• 104-86-9 4-chlorobenzylamine 
• 104-90-5 5-ethyl-2-methyl-pyridine 
• 6332-56-5 2-hydroxy-3-nitropyridine 

Downstream Products

• 42048-25-9 2-(4-Chlorophenylmethylamino)-3-aminopyridine 
• 136122-61-7 4-[3-(4-Chloro-benzyl)-3H-imidazo[4,5-b]pyridin-2-ylsulfanyl]-butyric acid ethyl ester 
• 144727-86-6 4-[3-(4-Chloro-benzyl)-3H-imidazo[4,5-b]pyridin-2-yl]-3,3-dimethyl-butyric acid ethyl ester 
• 136122-54-8 3-(4-Chloro-benzyl)-3H-imidazo[4,5-b]pyridine-2-thiol 

Relevant academic research and scientific papers

Heterocyclic compounds having anti-diabetic activity and their use

Compounds of formula (I): STR1 [wherein: X represents an unsubstituted or substituted indolyl, indolinyl, azaindolyl, azaindolinyl, imidazopyridyl or imidazopyrimidinyl group; Y represents an oxygen or sulfur atom; Z represents a 2,4-dioxothiazolidin-5-ylidenylmethyl, 2,4-dioxothiazolidin-5-ylmethyl, 2,4-dioxooxazolidin-5-ylmethyl, 3,5-dioxooxadiazolidin-2-ylmethyl or N-hydroxyureidomethyl group; R represents a hydrogen atom, an alkyl group, an alkoxy group, a halogen atom, a hydroxy group, a nitro group, an aralkyl group or a unsubstituted or substituted amino group; and m is an integer of from 1 to 5] have hypoglycemic and anti-diabetic activities.

Synthesis and Structure - Activity Relationships of Novel Benzimidazole and Imidazopyridine Acid Derivatives as Thromboxane A2 Receptor Antagonists

A series of 1-benzylbenzimidazole and 3-benzylimidazopyridine substituted in the 2-position by an alkanoic or mercaptoalkanoic acid chain was synthesized for evaluation as potential thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonists.T

AZABENZIMIDAZOLE DERIVATIVES WHICH ARE THROMBOXANE RECEPTOR ANTAGONISTS

The present invention relates to the derivatives of the formula STR1 in which: A is an aromatic ring or a nitrogen heterocycle;X 1, X 2, X 3 and X 4 are independently a hydrogen atom, a halogen atom, a lower alkyl radical, a C. sub.3-C 7 cycloalkyl

BENZIMIDAZOLE AND AZABENZIMIDAZOLE DERIVATIVES WHICH ARE THROMBOXANE RECEPTOR ANTAGONISTS, THEIR METHODS OF PREPARATION

The present invention relates to the derivatives of the formula STR1 where the substituents are defined in the specification. These compounds possess thromboxane receptor antagonist properties.

Noval benzimidazole and azabenzimiazole derivatives which are thromboxane receptor antagonists, their methods of preparation and pharmaceutical compositions in which they are present

The present invention relates to the derivatives of the formula STR1 in which: A is an aromatic ring or a nitrogen heterocycle;X 1, X 2, X 3 and X 4 are independently a hydrogen atom, a halogen atom, a lower alkyl radical, an alkoxy radical, an alkylthio