373356-35-5Relevant academic research and scientific papers
Regioselective ortho alkylation of nitro indole, carbazole, benzothiophene and benzofuran
Lamont, Scott G.,Donald, Craig S.,Lyman Feron,Groombridge, Sam D.
, p. 7165 - 7167 (2015)
Substituted indoles, carbazoles, benzothiophenes and benzofurans are important motifs in the pharmaceutical industry. Herein we report a novel, regioselective method to introduce alkyl substituents into position ortho of nitro groups by the addition of a Grignard reagent followed by subsequent oxidation with DDQ.
Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by np y5 receptor
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Page 52, (2010/02/05)
Compounds of formula (I): wherein: X is a group of formula (A) or (B): and R1, R2, R3, R4, n, x, y and z are as defined within are described. Processes for their preparation and their use in the treatment of disorders mediated by the neuropeptide Y5 receptor in a warm-blooded animal, such as a human being are also described.
