373606-47-4

Upstream product

• 100-39-0 benzyl bromide 
• 143697-28-3 Pent-4-enyl 3,4-O-isopropylidene-β-L-fucopyranoside 
• 821-09-0 n-Pent-4-enyl alcohol 
• 676518-78-8 1-O-(4-pentenyl) 2,3,4-tri-O-acetyl-β-L-fucopyranoside 
• 143416-55-1 1-O-(4-pentenyl) β-L-fucopyranoside 
• 16741-27-8 2,3,4-tri-O-acetyl-α-L-fucopyranosyl bromide 

Downstream Products

• 373606-28-1 dibutyl 2-O-benzyl-3,4-di-O-pivaloyl-β-L-fucopyranoside phosphate 
• 373606-55-4 2-O-benzyl-3,4-di-O-pivaloyl-α-L-fucopyranosyl trichloroacetimidate 
• 373606-48-5 2,2-Dimethyl-propionic acid (2S,3S,4R,5R,6S)-3-benzyloxy-5-(2,2-dimethyl-propionyloxy)-6-methyl-2-pent-4-enyloxy-tetrahydro-pyran-4-yl ester 

Relevant academic research and scientific papers

Total Synthesis of Tri-, Hexa- and Heptasaccharidic Substructures of the O-Polysaccharide of Providencia rustigianii O34

A general and efficient strategy for synthesis of tri-, hexa- and heptasaccharidic substructures of the lipopolysaccharide of Providencia rustigianii O34 is described. For the heptasaccharide seven different building blocks were employed. Special features of the structures are an α-linked galactosamine and the two embedded α-fucose units, which are either branched at positions-3 and -4 or further linked at their 2-position. Convergent strategies focused on [4+3], [3+4], and [4+2+1] couplings. Whereas the [4+3] and [3+4] coupling strategies failed the [4+2+1] strategy was successful. As monosaccharidic building blocks trichloroacetimidates and phosphates were employed. Global deprotection of the fully protected structures was achieved by Birch reaction.

Oligosaccharide synthesis with glycosyl phosphate and dithiophosphate triesters as glycosylating agents

Described is an efficient one-pot synthesis of α- and β-glycosyl phosphate and dithiophosphate triesters from glycals via 1,2-anhydrosugars. Glycosyl phosphates function as versatile glycosylating agents for the synthesis of β-glucosidic, β-galactosidic,