373623-22-4

Basic information

• Product Name: N-allyl-N-methyl-3-bromoaniline
• Synonyms: N-allyl-N-methyl-3-bromoaniline
• CAS NO: 373623-22-4
• Molecular Weight: 226.116
• Mol File: 373623-22-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: N-allyl-N-methyl-3-bromoaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-allyl-N-methyl-3-bromoaniline(373623-22-4)
• EPA Substance Registry System: N-allyl-N-methyl-3-bromoaniline(373623-22-4)

Safety Data

• Hazardous Substances Data: 373623-22-4(Hazardous Substances Data)

Upstream product

• 591-19-5 m-Bromoaniline 
• 66584-32-5 3-bromo-N-methylaniline 
• 106-95-6 allyl bromide 

Relevant articles and documents

Spontaneously Blinking Fluorophores Based on Nucleophilic Addition/Dissociation of Intracellular Glutathione for Live-Cell Super-resolution Imaging

Single-molecule localization microscopy (SMLM) allows the reconstruction of super-resolution images but generally requires prior intense laser irradiation and in some cases additives to induce blinking of conventional fluorophores. We previously introduced a spontaneously blinking rhodamine fluorophore based on an intramolecular spirocyclization reaction for live-cell SMLM under physiological conditions. Here, we report a novel principle of spontaneous blinking in living cells, which utilizes reversible ground-state nucleophilic attack of intracellular glutathione (GSH) upon a xanthene fluorophore. Structural optimization afforded two pyronine fluorophores with different colors, both of which exhibit equilibrium (between the fluorescent dissociated form and the nonfluorescent GSH adduct form) and blinking kinetics that enable SMLM of microtubules or mitochondria in living cells. Furthermore, by using spontaneously blinking fluorophores working in the near-infrared (NIR) and green ranges, we succeeded in dual-color live-cell SMLM without the need for optimization of the imaging medium.

SUPER-RESOLUTION FLUORESCENT IMAGING PROBE

[Problem] To provide a novel fluorescent probe for super-resolution imaging that uses fluorescent light emission characteristics that originate from an intermolecular nucleophilic addition-dissociation equilibrium reaction, and to provide a super-resoluti

Studies in amine oxide rearrangement: Meisenheimer rearrangement of m-substituted tertiary amine oxides

A number of N-substituted but-2-ynyl, allyl and 4-aryloxy-2-butynyl-N- methyl anilines 2a-c, 3a-h and 5d-f have been synthesized in excellent yield. The m-substituted allylalkylaryl amines have been then treated with one equivalent of m-chloroperoxybenzoi