3737-57-3Relevant articles and documents
The organic acid acylating the amino group having a continuous method
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Paragraph 0077-0079, (2017/02/24)
The invention relates to a continuous method for N-acylating amino group-carrying organic acids by reacting at least one carboxylic acid of formula (I) R1—COOH (I), wherein R1 represents hydrogen or an optionally substituted hydrocarbon group with 1 to 50 carbon atoms, with at least one at least one amino group-carrying organic acid of formula (II) R2NH-A-X (II), wherein A represents an optionally substituted hydrocarbon group with 1 to 50 carbon atoms, X represents an acid group or the metal salt thereof and R2 represents hydrogen, an optionally substituted hydrocarbon group with 1 to 50 C atoms or a group of the formula -A-X, wherein A and X independently are defined as above, in a reaction tube the longitudinal axis of which extends in the direction of propagation of the microwaves of a monomode microwave applicator, under microwave irradiation to form amide.