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1,1-Diphenyl-2-(α-methylbenzylidene)hydrazine is an organic compound with the chemical formula C22H21N. It is a derivative of hydrazine, featuring a diphenyl group (two phenyl rings) and an α-methylbenzylidene group (a benzylidene group with an α-methyl substitution). 1,1-Diphenyl-2-(α-methylbenzylidene)hydrazine is known for its potential applications in the synthesis of various pharmaceuticals and agrochemicals, particularly as an intermediate in the production of certain anti-inflammatory and antipyretic drugs. It is also used in the preparation of dyes and pigments. Due to its reactivity, it is important to handle 1,1-Diphenyl-2-(α-methylbenzylidene)hydrazine with care, following proper safety protocols to minimize health and environmental risks.

3741-90-0

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3741-90-0 Usage

Physical state

Yellow-orange solid

Melting point

126-128°C

Usage

Reagent in organic synthesis

Reaction with diazonium salts

Forms azo compounds

Biological properties

Exhibits antifungal and antitumor properties

Pharmaceutical research

Of interest due to its biological properties

Potential treatment

Studied for use in tuberculosis treatment

Hazardous nature

Potentially toxic compound

Safety precautions

Appropriate safety measures should be taken when handling

Check Digit Verification of cas no

The CAS Registry Mumber 3741-90-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,7,4 and 1 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 3741-90:
(6*3)+(5*7)+(4*4)+(3*1)+(2*9)+(1*0)=90
90 % 10 = 0
So 3741-90-0 is a valid CAS Registry Number.
InChI:InChI=1/C20H18N2/c1-17(18-11-5-2-6-12-18)21-22(19-13-7-3-8-14-19)20-15-9-4-10-16-20/h2-16H,1H3/b21-17-

3741-90-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-phenyl-Ethanone, 2,2-diphenylhydrazone

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3741-90-0 SDS

3741-90-0Relevant academic research and scientific papers

Synthesis of isoquinolines via Rh(III)-catalyzed C-H activation using hydrazone as a new oxidizing directing group

Chuang, Sheng-Chieh,Gandeepan, Parthasarathy,Cheng, Chien-Hong

supporting information, p. 5750 - 5753 (2013/12/04)

An efficient and mechanistically interesting method for the synthesis of highly substituted isoquinolines by a Rh(III)-catalyzed hydrazone directed ortho C-H bond activation and annulation without an external oxidant is described. This reaction is accomplished via a C-C and C-N bond formation along with N-N bond cleavage.

Inhibiteurs mixtes des voies de la cyclooxygenase et des lipoxygenases: synthese et activite de derives hydrazoniques

Ghiglieri-Bertez, Chantal,Coquelet, Claude,Alazet, Alain,Bonne, Claude

, p. 147 - 152 (2007/10/02)

Dual inhibitors of the cyclooxygenase and lipoxygenase pathways: synthesis and activity of hydrazone derivatives.Non-steroidal anti-inflammatory drugs (NSAIDs) act by preventing prostaglandin production.In recent years, research on non-steroid dual inhibitors of prostaglandin and leukotriene biosyntheses has been developed.These compounds should represent a new class of anti-inflammatory drugs, with a wider spectrum of activity than classical NSAIDs.The present paper reports the synthesis of hydrazone derivatives.The effect of various substitutions is studied on platelet cyclooxygenase (i.e. prostaglandin synthesis) and on leukocyte 5-lipoxygenase (i.e. leukotriene synthesis).Among the 50 tested compounds, 2 hydrazone derivatives were selected for their significant dual inhibitory potency: 2-acetylthiophene-2-thiazolylhydrazone 5g, and N-phenyl benzimidrazone 6c.Keywords - non-steroidal anti-inflammatory drugs / hydrazones / dual inhibitor / cyclooxygenase / lipoxygenase

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