37428-97-0

Usage

Uses

Used in Organic Electronics:
2,4,5-triphenylpyrimidine is used as a key component in the development of organic electronic devices, such as organic photovoltaics (OPVs) and organic light-emitting diodes (OLEDs). Its unique structure and properties contribute to the performance and efficiency of these devices, making it a valuable material in the field of organic electronics.
Used in Pharmaceutical Synthesis:
2,4,5-triphenylpyrimidine is used as a pharmaceutical intermediate for the synthesis of biologically active compounds. Its chemical structure provides a foundation for the creation of new drugs, potentially leading to advancements in medicine and healthcare. 2,4,5-triphenylpyrimidine's versatility in chemical reactions allows for the exploration of various therapeutic applications.

Upstream product

• 122372-10-5 2,5-dichloro-4-phenylpyrimidine 
• 5750-76-5 2,4,5-trichloropyrimidine 
• 98-80-6 phenylboronic acid 
• 901311-75-9 5-chloro-2,4-diphenylpyrimidine 
• 119072-55-8 tert-butylisonitrile 
• 1670-14-0 benzamidine monohydrochloride 
• 501-65-5 diphenyl acetylene 
• 901311-78-2 4-methoxy-2,5-diphenylpyrimidine 
• 901311-79-3 5-chloro-4-methoxy-2-phenylpyrimidine 
• 901311-77-1 2-chloro-4-methoxy-5-phenylpyrimidine 
• 153391-51-6 4-chloro-2,5-diphenylpyrimidine 

Relevant academic research and scientific papers

Titanium catalyzed one-pot multicomponent coupling reactions for direct access to substituted pyrimidines

A titanium-catalyzed 3-component coupling reaction can be used to generate tautomers of 1,3-diimines. These diimines produced in situ undergo condensation with amidines in a one-pot procedure to provide substituted pyrimidines. Seventeen examples of pyrimidines are provided using this one-pot, 4-component procedure from simple starting materials. In some cases, catalyst architecture can be tuned to control the regioselectivity of the alkyne addition. Finally, the regioselectivity of amidine addition to unsymmetrical 1,3-diimines is discussed.

Microwave-assisted, efficient and regioselective Pd-catalyzed C-phenylation of halopyrimidines

We herein report that flash heating microwave irradiation is a helpful tool in the formation of arylpyrimidines from the corresponding halopyrimidines. The palladium-catalyzed cross-coupling reactions of 2,4-di- and 2,4,5-trihalopyrimidines with phenylboronic acid under the above conditions are described. By use of the appropriate catalyst and the adequate halopyrimidine, good regioselectivity can be achieved in the 2-, 4-, or 5-positions of the heterocycle. In addition, we show that this methodology is ameneable for the stepwise preparation of mono-, di-, and triphenylpyrimidines.