37447-08-8Relevant academic research and scientific papers
Antitumor Imidazotetrazines. 20. Preparation of the 8-Acid Derivative of Mitozolomide and Its Utility in the Preparation of Active Antitumor Agents
Horspool, K. R.,Stevens, M. F. G.,Newton, C. G.,Lunt, E.,Walsh, R. J. A.,et al.
, p. 1393 - 1399 (1990)
The preparation of 3-(2-chloroethyl)-4-oxo-3H-imidazo-1,2,3,5-tetrazine-8-carboxylic acid, a key derivative of mitozolomide in our exploration of the structure-activity relationships of this class of antitumor agents, is described.The facile conver
