Journal of Medicinal Chemistry p. 1393 - 1399 (1990)
Update date:2022-09-26
Topics:
Horspool, K. R.
Stevens, M. F. G.
Newton, C. G.
Lunt, E.
Walsh, R. J. A.
et al.
The preparation of 3-(2-chloroethyl)-4-oxo-3H-imidazo<5,1-d>-1,2,3,5-tetrazine-8-carboxylic acid, a key derivative of mitozolomide in our exploration of the structure-activity relationships of this class of antitumor agents, is described.The facile conver
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