37447-35-1 Usage
General Description
(Benzyloxycarbonylamino)malonic acid dimethyl ester, also known as BOC-AA-Mal-OMe, is a chemical compound commonly used in organic synthesis as a protective group for amino acids. It is an ester derivative of malonic acid with two methyl groups and a carbonyl group, as well as a benzyloxycarbonyl (BOC) protecting group attached to the amino group. (Benzyloxycarbonylamino)malonic acid dimethyl ester is often used in peptide synthesis to protect the amino group of an amino acid, which allows for selective reactions to occur at other functional groups within the molecule. BOC-AA-Mal-OMe is a versatile tool for chemists involved in peptide and pharmaceutical synthesis, as it helps to control reactions and protect sensitive functional groups during the synthesis process.
Check Digit Verification of cas no
The CAS Registry Mumber 37447-35-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,4,4 and 7 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 37447-35:
(7*3)+(6*7)+(5*4)+(4*4)+(3*7)+(2*3)+(1*5)=131
131 % 10 = 1
So 37447-35-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H15NO6/c1-18-11(15)10(12(16)19-2)14-13(17)20-8-9-6-4-3-5-7-9/h3-7,10H,8H2,1-2H3,(H,14,17)
37447-35-1Relevant articles and documents
Total synthesis of the duocarmycins
Yamada, Ken,Kurokawa, Toshiki,Tokuyama, Hidetoshi,Fukuyama, Tohru
, p. 6630 - 6631 (2007/10/03)
The total synthesis of (+)-duocarmycin A and SA through a common indoline intermediate is described. The key reactions include selective lithiation of a 2,6-dibromoiodobenzene derivative and diastereoselective addition to a chiral nitroalkene, copper-mediated aryl amination, and addition of aryllithium to azlactones. Copyright
Structure taste relationships of L aspartyl aminomalonic acid diesters
Fujino,Wakimasu,Mano,Tanaka,Nakajima
, p. 2112 - 2117 (2007/10/13)
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