374633-75-7Relevant academic research and scientific papers
Synthesis and biological activities of novel β-carbolines as PDE5 inhibitors
Sui, Zhihua,Guan, Jihua,Macielag, Mark J.,Jiang, Weiqin,Qiu, Yuhong,Kraft, Patricia,Bhattacharjee, Sheela,John, T. Matthew,Craig, Elizabeth,Haynes-Johnson, Donna,Clancy, Joanna
, p. 761 - 765 (2007/10/03)
A series of N2-furoyl and N2pyrimidinyl β-carbolines was discovered to possess potent inhibitory activity against PDE5. During the synthesis we developed a tandem resin quenching protocol, which allowed us to synthesize large number
SUBSTITUTED PYRROLOPYRIDINONE DERIVATIVES USEFUL AS PHOSPHODIESTERASE INHIBITORS
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, (2008/06/13)
The invention relates to novel pyrrolopyridinone derivatives of the formula (I) or (II): pharmaceutical compositions containing the compounds and their use for the treatment of sexual dysfunction
