37472-51-8

Basic information

• Product Name: Butanoic acid, 2-oxo-, 1,1-dimethylethyl ester
• Synonyms: tert-butyl 2-oxybutanoate;Butanoic acid,2-oxo-,1,1-dimethylethyl ester;t-butyl 2-oxobutanoate;2-Oxobuttersaeure-tert.-butylester;tert-butyl 2-oxobutyrate
• CAS NO: 37472-51-8
• Molecular Formula: C8H14O3
• Molecular Weight: 158.19500
• Mol File: 37472-51-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 198.8±9.0 °C(Predicted)
• Density: 0.981±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Butanoic acid, 2-oxo-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 2-oxo-, 1,1-dimethylethyl ester(37472-51-8)
• EPA Substance Registry System: Butanoic acid, 2-oxo-, 1,1-dimethylethyl ester(37472-51-8)

Safety Data

• Hazardous Substances Data: 37472-51-8(Hazardous Substances Data)

Upstream product

• 177540-34-0 2-(Methyl-p-tolyl-hydrazono)-butyric acid tert-butyl ester 

Downstream Products

• 206996-51-2 (R)-2-hydroxy-butyric acid tert-butyl ester 
• 37787-90-9 (S)-tert-butyl 2-hydroxybutanoate 
• 1218815-56-5 (3R,4R)-tert-butyl 3-methyl-5-nitro-2-oxo-4-phenylpentanoate 
• 1245908-00-2 (3S,4S)-tert-butyl 3-methyl-5-nitro-2-oxo-4-phenylpentanoate 
• 1643582-66-4 C₃₁H₂₃NO₄ 

Relevant articles and documents

Electrophilic α-p-tolylhydrazonylation of tert-butyl alkanoates and tertiary alkanamides with tert-butyl p-tolylazo sulfide

The reactions of the enolates of tert-butyl alkanoates 2 and N,N-dialkylalkanamides 3 with tert-butyl p-tolylazo sulfide 1 in THF furnish good yields of the corresponding α-p-tolylhydrazonylated esters 4 and amides 5. Results are reported showing the possible transformation of 4 and 5 into the N-methylated derivatives 8 and 9 and the subsequent deblocking of the protected carbonyl function to the corresponding 2-oxoalkanoates 10 and 2-oxoalkanamides 11.