374822-25-0

Basic information

• Product Name: (RS)-1-[3,5-Bis(trifluoromethyl)phenyl]-1.2-ethanediol
• Synonyms: (RS)-1-[3,5-Bis(trifluoromethyl)phenyl]-1.2-ethanediol
• CAS NO: 374822-25-0
• Molecular Weight: 274.163
• Mol File: 374822-25-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (RS)-1-[3,5-Bis(trifluoromethyl)phenyl]-1.2-ethanediol(CAS DataBase Reference)
• NIST Chemistry Reference: (RS)-1-[3,5-Bis(trifluoromethyl)phenyl]-1.2-ethanediol(374822-25-0)
• EPA Substance Registry System: (RS)-1-[3,5-Bis(trifluoromethyl)phenyl]-1.2-ethanediol(374822-25-0)

Safety Data

• Hazardous Substances Data: 374822-25-0(Hazardous Substances Data)

Upstream product

• 349-59-7 3,5-bis(trifluoromethyl)styrene 

Downstream Products

• 374822-26-1 (RS)-1-[3,5-bis(trifluoromethyl)-α-{[2-(trimethylsilyl)ethoxy]methoxymethyl}benzenemethanol] 

Relevant articles and documents

Ru-MACHO-Catalyzed Highly Chemoselective Hydrogenation of α-Keto Esters to 1,2-Diols or α-Hydroxy Esters

A ruthenium pincer catalyst has been shown to be highly effective for the hydrogenation of a wide range of α-keto esters, affording either diols or hydroxy esters depending on the choice of reaction conditions. Strong base, high temperature, and pressure favor the formation of diols whilst the opposite is true for the hydroxy esters.