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1,2,3,4-Tetrahydro-2-[5-(3,4-dimethoxyphenyl)-pyrimidin-2-yl]-3-(3,4-methylenedioxyphenyl)-9H-pyrrolo-[3,4-b]quinolin-9-one is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

374926-75-7

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374926-75-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 374926-75-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,4,9,2 and 6 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 374926-75:
(8*3)+(7*7)+(6*4)+(5*9)+(4*2)+(3*6)+(2*7)+(1*5)=187
187 % 10 = 7
So 374926-75-7 is a valid CAS Registry Number.

374926-75-7Relevant academic research and scientific papers

Pyrimidinylpyrroloquinolones as highly potent and selective PDE5 inhibitors for treatment of erectile dysfunction

Sui, Zhihua,Guan, Jihua,Macielag, Mark J.,Jiang, Weiqin,Zhang, Suying,Qiu, Yuhong,Kraft, Patricia,Bhattacharjee, Sheela,John, T. Matthew,Haynes-Johnson, Donna,Clancy, Joanna

, p. 4094 - 4096 (2007/10/03)

A series of N-pyrimidinylpyrroloquinolones were discovered as extremely potent and selective PDE5 inhibitors. Representative compounds demonstrated in vivo efficacy in dog erectile dysfunction models and are orally bioavailable.

SUBSTITUTED PYRROLOPYRIDINONE DERIVATIVES USEFUL AS PHOSPHODIESTERASE INHIBITORS

-

, (2008/06/13)

The invention relates to novel pyrrolopyridinone derivatives of the formula (I) or (II): pharmaceutical compositions containing the compounds and their use for the treatment of sexual dysfunction

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