375-03-1

Basic information

• Product Name: HEPTAFLUORO-1-METHOXYPROPANE
• Synonyms: HEPTAFLUOROPROPYL METHYL ETHER;HEPTAFLUORO-1-METHOXYPROPANE;1,1,1,2,2,3,3-Heptafluoro-3-methoxypropane;1,1,1,2,2,3,3-heptafluoro-3-methoxy-Propane;Heptafluoropropylmethylether98%;1,1,1,2,2,3,3-heptafluoro-3-methoxy-Propan;Propane,1,1,1,2,2,3,3-heptafluoro-3-methoxy-;Perfluoropropyl methyl ether
• CAS NO: 375-03-1
• Molecular Formula: C₄H₃F₇O
• Molecular Weight: 200.05
• Product Categories: refrigerants
• Mol File: 375-03-1.mol
• Article Data: 8

Chemical Properties

• Melting Point: -123
• Boiling Point: 34
• Flash Point: °C
• Appearance: /
• Density: 1.409
• Refractive Index: 1.3597 (estimate)
• CAS DataBase Reference: HEPTAFLUORO-1-METHOXYPROPANE(CAS DataBase Reference)
• NIST Chemistry Reference: HEPTAFLUORO-1-METHOXYPROPANE(375-03-1)
• EPA Substance Registry System: HEPTAFLUORO-1-METHOXYPROPANE(375-03-1)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 375-03-1(Hazardous Substances Data)

Usage

Uses

Heptafluoro-1-methoxypropane is used in preparation method of Isolated Hydrofluoroether.

Upstream product

• 116-15-4 perfluoropropylene 
• 36336-08-0 methyl hypofluorite 
• 428-59-1 Hexafluoropropene oxide 
• 77-78-1 dimethyl sulfate 
• 422-61-7 perfluoropropanoyl fluoride 
• 616-38-6 carbonic acid dimethyl ester 
• 666-92-2 Ethyl pentafluoro-1-propenyl ether 
• 1538-06-3 methyl fluoroformate 
• 64-17-5 ethanol 
• 132182-90-2 2,3-bis(fluorosulfato)perfluoro-(2-methylpentane) 

Downstream Products

• 1620006-34-9 N,N,N-trimethyl-1-phenylmethanaminium perfluoropropoxide 
• 353-50-4 Carbonyl fluoride 
• 422-61-7 perfluoropropanoyl fluoride 
• 271257-42-2 heptafluoropropionyl formate 

Relevant articles and documents

Preparation method of isolated hydrofluoroether

The invention discloses a preparation method of isolated hydrofluoroether. The preparation method comprises the following steps: in the presence of inorganic fluoride and a co-catalyst, carrying out an alkylation reaction on perfluorinated epoxide and an alkylation reagent in an aprotic polar solvent to obtain the isolated hydrofluoroether. The main raw material perfluorinated epoxide can be prepared by epoxidation of perfluoro-olefin, the raw materials are simple and easy to obtain, the cost is lower than that of perfluorohexanone and perfluoroacyl fluoride compounds, the stability is good, the subsequent reaction is facilitated, and the quality can be ensured. The preparation method has the advantages that the reaction speed is high, the reaction time is short, the raw materials can be completely converted within 3-5 hours, the residual quantity of the raw material perfluorinated epoxy compound in the obtained crude product can be as low as 0.1% or below, and the reaction conversionrate is high. The content of the target product can reach 97% or above, the reaction selectivity is high, the byproducts are few, and the method is suitable for industrial application.

Hydrofluoroether synthetic method

The invention discloses a hydrofluoroether synthetic method which comprises the following steps of throwing vinyl ether, a solvent and a composite fluoride agent in a reactor, rising the temperature to a temperature required for reaction to perform reaction, and separating a reaction liquid to obtain a hydrofluoroether product, wherein the molar ratio of the vinyl ether, the solvent and the composite fluoride agent is 1 to (1-3) to (1-2), the reaction temperature is 50-150 DEG C, and the reaction time is 2-5h. According to the hydrofluoroether synthetic method provided by the invention, the composite fluoride agent is used to perform synthesis of the hydrofluoroether, fluorination addition can be efficiently performed at lower temperature, the yield is larger than 90 percent, and the deficiencies of the traditional synthetic technology are effectively solved.

Methyl hypofluorite (MeOF) reactions with various fluoroolefins

The reaction of methyl hypofluorite (MeOF) with certain fluoroolefins, such as CF2=CF2, CF2=CFCF3, CF2=CFOCF3, CF2=CFOMe, CF2=CClF, CF2=CHF, CF2=CH2, CHF=CH2, CF2=CFCF=CF2, occurred in CD3CN or in the presence of NaF. Using neat MeOF in the presence of NaF was a novel method and gave good results. We observed that when more than three fluorine atoms are bonded to the C-C double bond, the addition products were obtained in mostly good yields.