37528-39-5 Usage
Structure
Derivative of quinazolinone with a benzene ring fused to a pyrimidine ring
Substituents
A methoxy group at the 7th position and a methyl group at the 4th position of the quinazolinone core structure
Use in pharmaceutical industry
Commonly used for the synthesis of various drugs and biologically active compounds
Versatility
Has versatile chemical properties and potential therapeutic applications
Biological activities
Studied for its potential anti-inflammatory and anticancer properties, making it an interesting target for further research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 37528-39-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,5,2 and 8 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 37528-39:
(7*3)+(6*7)+(5*5)+(4*2)+(3*8)+(2*3)+(1*9)=135
135 % 10 = 5
So 37528-39-5 is a valid CAS Registry Number.
37528-39-5Relevant articles and documents
Central Nervous System Active Compounds. XIV On the Cyclization of N-Acyl-N'-arylureas
Heinicke, Grant,Hung, Tran V.,Prager, Rolf H.,Ward, A. David
, p. 831 - 844 (2007/10/02)
The cyclization of N-acyl-N'-arylureas in polyphosphoric acid has been reinvestigated.The product is not only the 4-substituted quinazolin-2(1H)-one as reported, but also contains the 2-acylaniline in major proportions.Two minor products have also been isolated.At 80 deg, an intermediate has been detected, the properties of which are consistent with it being the corresponding 2-acylphenylurea.Acyl ureas with strongly electron-withdrawing acyl groups from major amount of the corresponding anilide by the formal loss of cyanic acid.The application of this reaction tothe synthesis of quinazolinylphthalides has been investigated.
