375366-22-6

Basic information

• Product Name: (R)-5,6-dihydro-5-hydroxy-N-(1-oxo-3-phenylpropyl)-2(1H)-pyridone
• Synonyms: (R)-5,6-dihydro-5-hydroxy-N-(1-oxo-3-phenylpropyl)-2(1H)-pyridone
• CAS NO: 375366-22-6
• Molecular Weight: 245.278
• Mol File: 375366-22-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-5,6-dihydro-5-hydroxy-N-(1-oxo-3-phenylpropyl)-2(1H)-pyridone(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-5,6-dihydro-5-hydroxy-N-(1-oxo-3-phenylpropyl)-2(1H)-pyridone(375366-22-6)
• EPA Substance Registry System: (R)-5,6-dihydro-5-hydroxy-N-(1-oxo-3-phenylpropyl)-2(1H)-pyridone(375366-22-6)

Safety Data

• Hazardous Substances Data: 375366-22-6(Hazardous Substances Data)

Upstream product

• 108-05-4 vinyl acetate 
• 375366-20-4 (+/-)-5,6-dihydro-5-hydroxy-N-(1-oxo-3-phenylpropyl)-2(1H)-pyridone 
• 375366-19-1 (+/-)-4,5-epoxy-N-(1-oxo-3-phenylpropyl)-3,4,5,6-tetrahydro-2(1H)-pyridone 
• 375366-18-0 3,6-dihydro-N-(1-oxo-3-phenylpropyl)-2(1H)-pyridone 
• 61892-77-1 1,6-dihydropyridin-2(3H)-one 
• 72717-68-1 N-allyl-3-butenamide 

Downstream Products

• 375366-21-5 (5R)-5-[(tert-butyldimethylsilyl)oxy]-N-(1-oxo-3-phenylpropyl)-3,4,5,6-tetrahydro-2(1H)-pyridone 
• 375797-99-2 (R)-5-acetoxy-5,6-dihydro-N-(1-oxo-3-phenylpropyl)-2(1H)-pyridone 

Relevant articles and documents

Facile enantiodivergent approach to 5-hydroxy-5,6-dihydro-2(1H)-pyridones. First total synthesis of both enantiomers of pipermethystine.

[reaction: see text]. A novel enantiodivergent approach to 5-hydroxy-5,6-dihydro-2(1H)-pyridones using a ring closing metathesis and a lipase-mediated kinetic resolution as key steps is described and applied to the first synthesis of both enantiomers of pipermethystine.