37542-14-6

Basic information

• Product Name: 3(2H)-Benzofuranone, 2-(phenylmethylene)-, (Z)-
• CAS NO: 37542-14-6
• Molecular Formula: C15H10O2
• Molecular Weight: 222.243
• Mol File: 37542-14-6.mol
• Article Data: 74

Chemical Properties

• CAS DataBase Reference: 3(2H)-Benzofuranone, 2-(phenylmethylene)-, (Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3(2H)-Benzofuranone, 2-(phenylmethylene)-, (Z)-(37542-14-6)
• EPA Substance Registry System: 3(2H)-Benzofuranone, 2-(phenylmethylene)-, (Z)-(37542-14-6)

Safety Data

• Hazardous Substances Data: 37542-14-6(Hazardous Substances Data)

Upstream product

• 888-12-0 (E)-2'-hydroxy-chalcone 
• 16619-68-4 1-(2-hydroxyphenyl)-3-phenylprop-2-yn-1-one 
• 75630-75-0 (Z)-α-bromo-2'-hydroxychalcone 
• 39729-11-8 2'-hydroxychalcone dibromides 
• 108-91-8 cyclohexylamine 
• 39729-13-0 2'-acetoxychalcone dibromide 
• 72397-29-6 2'-acetoxy-α-bromo-β-methoxydihydrochalcone 
• 1214-47-7 1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one 
• 4940-48-1 rac-2-benzyl-2-hydroxy-2,3-dihydrobenzo[b]furan-3-one 
• 70188-29-3 trans-2,3-dihydro-3-nosyloxy-2-phenyl-4H-1-benzopyran-4-one 
• 1441-87-8 salicyloyl chloride 
• 1008105-79-0 (Z)-2-benzylidene-2,3-dihydrobenzofuran-3-ol 
• 7169-34-8 3-oxo-2,3-dihydrobenzo[b]furan 
• 100-52-7 benzaldehyde 

Relevant articles and documents

A new palladium-catalyzed synthesis of 3,4-disubstituted coumarins from 3- alkenoates of ortho-iodophenol, phenylacetylene and carbon monoxide

Palladium(0) has been found to catalyse the reaction of an aromatic carbon-iodide bond with carbon monoxide, the triple bond of alkynes and the allylic carbon of an ortho alkenoic chain to form a 3,4-disubstituted coumarin ring in satisfactory yield under

Palladium-catalyzed synthesis of coumarin

A palladium-catalyzed synthesis of coumarin, involving ring formation from o-iodophenol, norbornadiene, and carbon monoxide, followed by elimination of cyclopentadiene, is described, and contrasted with a new synthesis of aurone, based on the reaction of

Vinylcyclopropanes as All-Carbon 1,5-Dipoles: A Reactivity Switch for Palladium-Catalyzed (5 + 4) Cycloadditions

Azonanes were prepared by a palladium-catalyzed (5 + 4) cycloaddition between activated vinylcyclopropanes and 1-azadienes. During this process, the vinylcyclopropane partner displayed an unusual reactivity and behaved as an all-carbon 1,5-dipole. A N,N-bidentate ligand was required to inhibit the formation of thermodynamic (3 + 2) cycloadducts.

Design, synthesis and biological activities of dihydroaurones

To widen aurones applicability in achromatic food and cosmetic applications, a series of dihydroaurones were designed to mimic natural aurones as well as synthetic aurones. Dihydroaurones have been synthesized from the corresponding aurones by hydrogenation. These dihydroaurones and their corresponding aurones were screened for antioxidant, anti-inflammatory and tyrosinase enzyme inhibitory activity. Synthesized dihydroaurones (3b-f) displayed superior antioxidant activity in superoxide free radical scavenging assay than the standard gallic acid. Dihydroaurones (3b-f) also exhibited significant tyrosinase enzyme inhibitory activity and two dihydroaurones (3h, 3j) showed promising 5-lipoxygenase inhibitory activity.