37542-14-6

Upstream product

• 7169-34-8 3-oxo-2,3-dihydrobenzo[b]furan 
• 100-52-7 benzaldehyde 
• 16619-68-4 1-(2-hydroxyphenyl)-3-phenylprop-2-yn-1-one 
• 39729-11-8 2'-hydroxychalcone dibromides 
• 39729-13-0 2'-acetoxychalcone dibromide 
• 131968-25-7 2'-acetoxy-α-bromochalcone 
• 108-91-8 cyclohexylamine 
• 223511-19-1 1-[2-(tert-butyldimethylsilyloxy)phenyl]-3-phenylprop-2-yn-1-one 
• 1214-47-7 1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one 
• 90-02-8 salicylaldehyde 
• 109365-86-8 1-(o-hydroxyphenyl)-3-phenylpropargylic alcohol 
• 533-58-4 2-Iodophenol 
• 201230-82-2 carbon monoxide 
• 536-74-3 phenylacetylene 

Downstream Products

• 65-85-0 benzoic acid 
• 4265-14-9 2-benzylbenzofuran 
• 24114-57-6 3-(2-hydroxyphenyl)-1-phenyl-1-propene 
• 35405-25-5 trans-2-benzylidene-2H-benzofuran-3-one epoxide 
• 1391069-08-1 3-(4-phenylbenzofuro[3,2-b]pyridin-2-yl)coumarin 
• 1391069-02-5 3-(4-phenylbenzofuro[3,2-b]pyridin-2-yl)coumarin 
• 1391069-14-9 3-(4-phenylbenzofuro[3,2-b]pyridin-2-yl)coumarin 
• 141885-59-8 (2-Hydroxy-phenyl)-(2,4,5-triphenyl-2H-pyrazol-3-yl)-methanone 
• 75318-34-2 3-oxo-2-phenylmethylidene-2,3-dihydrobenzo[b]furan 

Relevant academic research and scientific papers

A new palladium-catalyzed synthesis of 3,4-disubstituted coumarins from 3- alkenoates of ortho-iodophenol, phenylacetylene and carbon monoxide

Palladium(0) has been found to catalyse the reaction of an aromatic carbon-iodide bond with carbon monoxide, the triple bond of alkynes and the allylic carbon of an ortho alkenoic chain to form a 3,4-disubstituted coumarin ring in satisfactory yield under

Selective palladium-catalyzed carbonylative synthesis of aurones with formic acid as the CO source

A general and practical strategy has been developed to prepare aurone derivatives. In the presence of the palladium catalyst, 2-iodophenol and terminal alkynes were reacted by using formic acid as the CO source with acetic anhydride as the additive. A var

Palladium-catalyzed synthesis of coumarin

A palladium-catalyzed synthesis of coumarin, involving ring formation from o-iodophenol, norbornadiene, and carbon monoxide, followed by elimination of cyclopentadiene, is described, and contrasted with a new synthesis of aurone, based on the reaction of

Vinylcyclopropanes as All-Carbon 1,5-Dipoles: A Reactivity Switch for Palladium-Catalyzed (5 + 4) Cycloadditions

Azonanes were prepared by a palladium-catalyzed (5 + 4) cycloaddition between activated vinylcyclopropanes and 1-azadienes. During this process, the vinylcyclopropane partner displayed an unusual reactivity and behaved as an all-carbon 1,5-dipole. A N,N-bidentate ligand was required to inhibit the formation of thermodynamic (3 + 2) cycloadducts.

A Palladium-Catalyzed Oxa-(4+4)-Cycloaddition Strategy towards Oxazocine Scaffolds

A Pd-catalyzed oxa-(4+4)-cycloaddition between 1-azadienes and (2-hydroxymethyl)allyl carbonates is described. Aurone-derived azadienes furnished polycyclic 1,5-oxazocines in good yields. Interestingly, linear azadienes have also been involved and yielded monocyclic heterocycles with complete regioselectivity. DFT calculations were carried out to gain insight on this observation.

Design, synthesis and biological activities of dihydroaurones

To widen aurones applicability in achromatic food and cosmetic applications, a series of dihydroaurones were designed to mimic natural aurones as well as synthetic aurones. Dihydroaurones have been synthesized from the corresponding aurones by hydrogenation. These dihydroaurones and their corresponding aurones were screened for antioxidant, anti-inflammatory and tyrosinase enzyme inhibitory activity. Synthesized dihydroaurones (3b-f) displayed superior antioxidant activity in superoxide free radical scavenging assay than the standard gallic acid. Dihydroaurones (3b-f) also exhibited significant tyrosinase enzyme inhibitory activity and two dihydroaurones (3h, 3j) showed promising 5-lipoxygenase inhibitory activity.

METHOD FOR SYNTHESIZING (Z)-AURONE AND DERIVATIVE COMPOUNDS THEREOF

One embodiment of the present invention is described below. Provided is (Z)-operon comprising o - (alkanone -1 - yl) phenol or its derivative compound in a thallium (Tl) catalyst and an cyclization step for cyclizing the compound under an organic solvent, and a method for producing the derivative compound.

Diversity-oriented synthesis of benzofuro[3,2-b]pyridine derivatives from aurone-derived α,β-unsaturated imines and activated terminal alkynes

An efficient annulation reaction of aurone-derived α,β-unsaturated imines and activated terminal alkynes mediated by triethylamine is described, which enables the facile synthesis of 1,4-dihydrobenzofuro[3,2-b]pyridines in high yields. When the nucleophil

Highly diastereoselective spiro-cyclopropanation of 2-arylidene-1,3-indanediones and dimethylsulfonium ylides

A highly diastereoselective spiro-cyclopropanation reaction of 2-arylidene-1,3-indanediones and dimethylsulfonium ylides has been developedviabase-induced annulation. This efficient and simple protocol features simple operations, mild conditions and excellent functional group compatibility. A variety of structurally interesting spiro-cyclopropanes were prepared in excellent yields and diastereomeric ratios (up to 97% yield and 20?:?1 dr). Also, ring expansion of the cyclopropanation product to quickly deliver a complex indeno[1,2-c]pyridazine structure showcased an interesting application of this method.

Preparation method of benzofurocoumarin compound

The invention discloses a preparation method of a photoactive benzofurocoumarin compound. The photoactive benzofurocoumarin compound is a compound shown as a formula I; the enantioselectivity of the compound shown in the formula I is up to 95-99%. The pho