37545-33-8

Usage

Uses

Used in Pharmaceutical Industry:
5-Methylpyrazine-2-carbohydrazide is used as a building block for the synthesis of various pharmaceuticals due to its versatile chemical structure and potential therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical industry, 5-Methylpyrazine-2-carbohydrazide is used as a precursor in the development of new agrochemicals, leveraging its chemical properties to create effective compounds for agricultural applications.
Used in Organic Chemistry:
5-Methylpyrazine-2-carbohydrazide is utilized in organic chemistry as a reagent or intermediate in the synthesis of a range of organic compounds, contributing to the advancement of chemical research and product development.
Used as an Anticancer Agent:
5-Methylpyrazine-2-carbohydrazide is studied for its potential as an anticancer agent, with research exploring its effects on various types of cancer and its possible integration into cancer treatment protocols.
Used for Antifungal and Antibacterial Properties:
5-METHYLPYRAZINE-2-CARBOHYDRAZIDE is also recognized for its antifungal and antibacterial properties, making it a candidate for use in applications requiring the control of microbial growth, such as in medical or industrial settings.

Upstream product

• 41110-34-3 5-methyl-2-pyrazine carboxylic acid ethyl ester 
• 5521-55-1 2-methylpyrazin-5-carboxylic acid 

Relevant academic research and scientific papers

Synthesis, characterization and biological screening of some novel pyrazine associated 1,2,4-triazoles

A new and efficient method has been developed for the synthesis of some novel pyrazine associated 1,2,4-triazoles e.g., 2-methyl-5-(4-alkyl/aryl-5-methylsulfanyl-4H-[1,2,4]-triazol-3-yl)-pyrazine (5a-c). This novel method involves 5-methyl-2-pyrazinecarbo

Pyrazine associated novel 1,2,4-triazolo thiadazines: Synthesis, characterization and as antibacterial agents

5-(5-Methyl-pyrazin-2-yl)-[1,3,4]-oxadiazole-2-thiol (4) has been synthesized form the starting material 5-methyl-2-pyrazinecarboxylic acid (1) on esterification with ethanol and condensation with hydrazine hydrate followed by cyclization with carbon disu

Synthesis and docking studies of pyrazine-thiazolidinone hybrid scaffold targeting dormant tuberculosis

The persistence of Mycobacterium tuberculosis (MTB) in dormant stage assists the pathogen to develop resistance against current antimycobactrial drugs. To address this issue, we report herein the synthesis of N-(4-oxo-2 substituted thiazolidin-3yl) pyrazi

3- (1,2,4-TRIAZOL-3YLALKYL) AZABRICLO (3.1.0) HEXANE DERIVATIVES AS MODULATORS OF DOPAMINE D3 RECEPTORS

The present invention relates to novel compounds of formula (I) or pharmaceutically acceptable salt thereof: wherein " G is selected from a group consisting of: phenyl, pyridyl, benzothiazolyl and indazolyl; " p is an integer ranging from 0 to 5; " R1 is independently selected from a group consisting of: halogen, hydroxy, cyano, C1-4alkyl, haloC1-4alkyl, C1-4alkoxy, haloC1-4alkoxy, C1-4alkanoyl and SF5, or corresponds to a group R5; " each R2 is independently hydrogen, fluorine or C1-4alkyl; " n is 2, 3, 4, or 5; " R3 is C1-4alkyl; " R4 is hydrogen, or a C1-4alkyl group, a benzyl group, a phenyl group, a heterocyclyl group, a 5- or 6-membered heteroaromatic group, or a 8- to 11-membered bicyclic group, any of which groups is optionally substituted by 1, 2, 3 or 4 substituents selected from the group consisting of: halogen, cyano, C1-4alkyl, haloC1-4alkyl, C1-4alkoxy, haloC1-4alkoxy, C1-4alkanoyl and SF5;or R4 is a -SR6 group; " R5 is selected from a group consisting of: isoxazolyl, -CH2-N-pyrrolyl, 1,1-dioxido-2-isothiazolidinyl, thienyl, thiazolyl, pyridyl and 2-pyrrolidinonyl, and such a group is optionally substituted by one or two substituents selected from a group consisting of: halogen, cyano, C1-4alkyl, haloC1-4alkyl, C1-4alkoxy and C1-4alkanoyl; " R6 is C1-4alkyl or -CH2C3-4cycloalkyl; and when R1 is chlorine and p is 1, such R1 is not present in the ortho position with respect to the linking bond to the rest of the molecule; and when R1 corresponds to R5, p is 1. processes for their preparation, intermediates used in these processes, pharmaceutical compositions containing them and their use in therapy, as modulators of dopamine D3 receptors, e.g. to treat drug dependency, as antipsychotic agents, to treat obsessive compulsive spectrum disorders, premature ejaculation or cognition impairment.