37558-57-9Relevant academic research and scientific papers
Catalytic c-c cleavage/alkyne-carbonyl metathesis sequence of cyclobutanones
Gao, Jiqiang,Liu, Chunhui,Li, Zhongjuan,Liang, Haotian,Ao, Yuhui,Zhao, Jinbo,Wang, Yuchao,Wu, Yuanqi,Liu, Yu
supporting information, p. 3993 - 3999 (2020/06/08)
A ring-opening/alkyne-carbonyl metathesis sequence of alkyne-tethered cyclobutanones catalyzed by AgSbF6 is realized for the first time to furnish multisubstituted naphthyl ketones under mild conditions. A range of substrates decorated with various substituents at different positions were all well accommodated. Preliminary mechanistic studies show that silver salt acted as a Lewis acid to facilitate both C-C cleavage of the cyclobutanone moiety and the subsequent metathesis between C═O and CC bonds.
