3756-35-2Relevant academic research and scientific papers
Transition metal free large-scale synthesis of aromatic vinyl chlorides from aromatic vinyl carboxylic acids using bleach
Hatvate, Navnath T.,Takale, Balaram S.,Ghodse, Shrikant M.,Telvekar, Vikas N.
supporting information, p. 3892 - 3894 (2018/10/02)
While continuing our research on Hunsdiecker reaction, we came across an interesting application of bleach, sodium hypochlorite (NaOCl) for decarboxylative chlorination reaction. The reaction is easily scaled up to 10 mmol. The reaction has good tolerance towards wide variety of functional groups. The reaction has mild conditions and gave relatively high chemical yield of the desired product.
Chloride-tolerant gold(I)-catalyzed regioselective hydrochlorination of alkynes
Ebule, Rene,Liang, Shengzong,Hammond, Gerald B.,Xu, Bo
, p. 6798 - 6801 (2017/11/09)
We have developed a highly regioselective homogeneous gold(I)-catalyzed anti-hydrochlorination of unactivated alkynes at room temperature. We have overcome the incompatibility between conventional cationic gold catalysts and chloride by using a hydrogen-b
