37560-50-2

Usage

Uses

Used in Pharmaceutical Industry:
1-(4-CHLOROPHENYL)-1H-PYRROLE-2-CARBALDEHYDE is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and functional groups make it a valuable building block for the development of new drugs with potential therapeutic applications.
Used in Dye and Pigment Industry:
1-(4-CHLOROPHENYL)-1H-PYRROLE-2-CARBALDEHYDE is used in the production of dyes and pigments. Its chemical properties allow it to be incorporated into various colorants, contributing to the development of a wide range of colors and shades for different applications.
Used in Research and Development:
1-(4-CHLOROPHENYL)-1H-PYRROLE-2-CARBALDEHYDE is employed as a research compound in the development of novel organic compounds. Its versatility in chemical reactions makes it an essential component in the exploration of new chemical pathways and the synthesis of innovative materials.

InChI:InChI=1/C11H8ClNO/c12-9-3-5-10(6-4-9)13-7-1-2-11(13)8-14/h1-8H

Upstream product

• 98-01-1 furfural 
• 106-47-8 4-chloro-aniline 
• 5044-38-2 1-(4-chlorophenyl)-1H-pyrrole 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 1160238-19-6 C₁₃H₁₃ClN₄S 
• 1160524-81-1 C₁₅H₁₇ClN₄S 
• 1160524-83-3 {1-[1-(4-chloro-phenyl)-pyrrol-2-ylmethyl]-pyrrolidin-2-yl}-methanol 

Relevant academic research and scientific papers

Selective and Efficient Formylation of Indoles (C3) and Pyrroles (C2) Using 2,4,6-Trichloro-1,3,5-Triazine/Dimethylformamide (TCT/DMF) Mixed Reagent

This study introduces an efficient method for the selective formylation of indoles and pyrroles at the positions of C(3) and C(2), respectively. The mixture of three equivalents of N,N-dimethylformamide and one equivalent of 2,4,6-trichloro-1,3,5-triazine (cyanuric chloride) generates an easy handling formylating agent for the efficient formylation of these classes of compounds to give the corresponding aldehydes under mild reaction conditions. This procedure was highly efficient, and a range of formylated indoles and pyrroles were obtained in good to excellent yields.

SYNTHESIS AND SPECTRAL PROPERTIES OF 1-ARYL-2-FORMYLPYRROLES

Various 1-aryl-2-formylpyrroles were synthesized by reaction of furfurol with substituted anilines.For p-bromo- and p-chlorophenyl substituents, the intermediate Schiff bases were isolated.

Reactions of Stenhouse Salts. III Transformation Products Under Acidic and Basic Conditions

Mild acid treatment of alcoholic solutions of Stenhouse salts has been shown to yield a mixture of the corresponding N-arylpyrrole-2-carbaldehyde and the N-aryl-3-hydroxypyridinium salt.Treatment of alcoholic solutions of the Stenhouse salts with a variety of bases leads to 4-substituted 2-arylaminocyclopent-2-enones.