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37567-78-5 Usage


1,5-Dimethoxy-1,4-cyclohexadiene, with the molecular formula C8H12O2, is a cyclic diene derivative of cyclohexene featuring two methoxy groups on carbon atoms one and four. This colorless liquid with a sweet odor is recognized for its reactivity and versatility in forming various chemical bonds, making it a significant intermediate in the chemical industry.


Used in Organic Synthesis:
1,5-Dimethoxy-1,4-cyclohexadiene is used as a building block in organic synthesis for the production of a wide range of pharmaceuticals and organic compounds. Its reactivity and ability to form different types of chemical bonds make it a valuable component in creating diverse products.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 1,5-Dimethoxy-1,4-cyclohexadiene is used as an intermediate for the synthesis of various drugs. Its unique structure and bonding capabilities allow for the development of new and innovative medications to address a variety of health concerns.
Used in Chemical Industry:
1,5-Dimethoxy-1,4-cyclohexadiene is also utilized in the chemical industry as an important intermediate for the production of a broad spectrum of products. Its versatility in forming chemical bonds contributes to the creation of numerous compounds used in various applications, from materials science to specialty chemicals.

Check Digit Verification of cas no

The CAS Registry Mumber 37567-78-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,5,6 and 7 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 37567-78:
155 % 10 = 5
So 37567-78-5 is a valid CAS Registry Number.

37567-78-5 Well-known Company Product Price

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  • Aldrich

  • (641111)  1,5-Dimethoxy-1,4-cyclohexadiene  96%

  • 37567-78-5

  • 641111-5G

  • 1,932.84CNY

  • Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017


1.1 GHS Product identifier

Product name 1,5-dimethoxycyclohexa-1,4-diene

1.2 Other means of identification

Product number -
Other names 2,5-Dihydroresorcinol dimethyl ether

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:37567-78-5 SDS

37567-78-5Downstream Products

37567-78-5Relevant articles and documents

Enantio- And Diastereoselective Construction of Contiguous Tetrasubstituted Chiral Carbons in Organocatalytic Oxadecalin Synthesis

Wada, Yuuki,Murata, Ryuichi,Fujii, Yuki,Asano, Keisuke,Matsubara, Seijiro

supporting information, p. 4710 - 4715 (2020/07/06)

The organocatalytic enantio- and diastereoselective cycloetherification of 1,3-cyclohexanedione-bearing enones involving the in situ generation of chiral cyanohydrins was developed. This transformation offers the first catalytic asymmetric approach to oxa

Enantio- and Diastereoselective Synthesis of Functionalized Carbocycles by Cu-Catalyzed Borylative Cyclization of Alkynes with Ketones

Zanghi, Joseph M.,Liu, Shuang,Meek, Simon J.

supporting information, p. 5172 - 5177 (2019/07/03)

A single-pot Cu-catalyzed enantio- and diastereoselective tandem hydroboration/borylative cyclization of alkynes with ketones for the synthesis of carbocycles is reported. The reaction proceeds via desymmetrization and generates four contiguous stereocent

Asymmetric Synthesis of Carbocyclic Propellanes

Schneider, Lisa M.,Schmiedel, Volker M.,Pecchioli, Tommaso,Lentz, Dieter,Merten, Christian,Christmann, Mathias

supporting information, p. 2310 - 2313 (2017/05/12)

A modular synthesis of functionalized carbocyclic propellanes was developed. Formation of the first of two quaternary bridgehead centers has been achieved by desymmetrization of prostereogenic ketones by either Hajos-Parrish-Eder-Sauer-Wiechert-type processes or Werner’s catalytic asymmetric Wittig reaction. The obtained bicyclic enones were subjected to conjugate additions upon which the remaining ring was formed by olefin metathesis. All bridges are amenable to further derivatization, which renders those compounds useful as central units in fragment-based drug discovery or as ligand scaffolds.

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