37568-86-8Relevant academic research and scientific papers
Copper-Catalyzed Oxidative Cyclization of Carboxylic Acids
Sathyamoorthi, Shyam,Du Bois
, p. 6308 - 6311 (2016)
A method for converting C-H to C-O bonds through oxidative cyclization of carboxylic acids to generate lactone products is described. The reaction employs catalytic amounts of Cu(OAc)2 and potassium persulfate as the terminal oxidant and is performed open to air in an aqueous acetic acid solvent system. Preliminary mechanistic studies suggest that substrate oxidation likely proceeds by sulfate radical anion and that the Cu catalyst has no influence on the product-determining step. These conclusions differ from related investigations that propose the intermediacy of a carboxylate radical.
Convenient syntheses of 3-aryl-3,4-dihydroisocoumarins and lunularic acid derivatives
Mali, Raghao S.,Shelke, Dattatray W.
, p. 822 - 825 (2007/10/02)
A convenient two-step approach for the syntheses of 3-aryl-3,4-dihydroisocoumarins (13-17) including some naturally occurring 3-aryl-8-hydroxy-3,4-dihydroisocoumarins (1,2) and lunularic acid derivatives (18-21) is described from 2-formylbenzoic acids (4,
