375826-30-5Relevant academic research and scientific papers
Troublesome alkoxythiophenes-mesomorphic behavior and highly efficient synthesis
Herbert, Mark R.,Sonpatki, Vaishali M.,Jakli, Antal,Seed, Alexander J.
, p. 181 - 188 (2007/10/03)
The synthesis of a novel ferroelectric alkoxythiophene-containing liquid crystal is described together with the mesophase morphology of the material. The alkoxythiophene unit is introduced by a highly efficient ring closure of an appropriate γ-ketoester using Lawesson's reagent as the sulfurating agent. Our new cyclization methodology represents the most efficient synthetic pathway for the synthesis of this unit. copy; 2001 OPA (Overseas Publishers Association) N.V. Published by license under the Gordon and Breach Science Publishers imprint, a member of the Taylor & Francis Group.
Troublesome alkoxythiophenes. A highly efficient synthesis via cyclization of γ-keto esters
Sonpatki,Herbert,Sandvoss,Seed
, p. 7283 - 7286 (2007/10/03)
A variety of alkoxythiophenes have been synthesized that represent ideal subunits for the synthesis of a new class of thermotropic liquid crystals via palladium-catalyzed cross-coupling reactions and organometallic derivatization. The methodology used represents the first highly efficient synthesis of alkoxythiophenes unlike previous pathways that have presented serious synthetic difficulties when the alkoxy chain consisted of more than four carbon atoms. The scope of the new procedure (relative to liquid crystalline intermediates) is presented and is compared and contrasted with the current literature.
