37584-92-2

Basic information

• Product Name: 1,3,4-Oxadiazole, 2-(2-furanyl)-5-(4-methoxyphenyl)-
• CAS NO: 37584-92-2
• Molecular Formula: C13H10N2O3
• Molecular Weight: 242.234
• Mol File: 37584-92-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,3,4-Oxadiazole, 2-(2-furanyl)-5-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,4-Oxadiazole, 2-(2-furanyl)-5-(4-methoxyphenyl)-(37584-92-2)
• EPA Substance Registry System: 1,3,4-Oxadiazole, 2-(2-furanyl)-5-(4-methoxyphenyl)-(37584-92-2)

Safety Data

• Hazardous Substances Data: 37584-92-2(Hazardous Substances Data)

Upstream product

• 100724-25-2 N'-((furan-2-yl)methylene)-4-methoxybenzohydrazide 
• 98-01-1 furfural 
• 3290-99-1 4-methoxybenzoic acid hydrazide 
• 824-94-2 p-methoxybenzyl chloride 
• 140-69-2 4-methoxybenzylhydrazine 
• 155164-68-4 4,5-Dichloro-2-(4-methoxy-benzoyl)-2H-pyridazin-3-one 

Relevant articles and documents

Metal-Free Synthesis of 1,3,4-Oxadiazoles from N′-(Arylmethyl)hydrazides or 1-(Arylmethyl)-2-(arylmethylene)hydrazines

An efficient and versatile metal-free synthesis of 1,3,4-oxadiazoles from N′-(arylmethyl)hydrazides or 1-(arylmethyl)-2-(arylmethylene)hydrazines through oxidative dehydrogenation is reported. A range of 2,5-disubstituted 1,3,4-oxadiazoles were prepared by treating N′-(arylmethyl)hydrazides with (diacetoxyiodo)benzene in acetonitrile or by treating 1-(arylmethyl)-2-(arylmethylene)hydrazines with [bis(trifluoroacetoxy)iodo]benzene in methyl tert-butyl ether. Aldehyde N-acylhydrazones and aldazines were initially generated in situ as intermediates.

Oxidative cyclization of aromatic aldehyde n-acylhydrazones by bis(trifluoroacetoxy)iodobenzene

Aromatic aldehyde N-acylhydrazones were oxidized into 2,5-disubstituted 1,3,4-oxadiazoles with bis(trifluoroacetoxy)iodobenzene in CHCl3 or DMSO at room temperature in good to excellent yields. Copyright Taylor & Francis Group, LLC.