375856-45-4

Upstream product

• 314283-98-2 (2-Methyl-3-nitro-phenyl)-[1-phenyl-meth-(Z)-ylidene]-amine 
• 100-52-7 benzaldehyde 

Downstream Products

• 448956-38-5 N-benzyl-N-(4-methoxycarbonylbenzyl)-2-methyl-3-nitroaniline 
• 709016-12-6 benzyl-(4-chloro-2-fluoro-benzyl)-(2-methyl-3-nitro-phenyl)-amine 
• 448956-69-2 N-[4-(allyloxy)benzyl]-N-benzyl-N-(2-methyl-3-nitrophenyl)amine 
• 448956-36-3 N,N-dibenzyl-N-(2-methyl-3-nitrophenyl)amine 

Relevant academic research and scientific papers

Discovery of novel nonsteroidal glucocorticoid receptor modulators

A new class of selective nonsteroidal glucocorticoid receptor modulators typified by N-{3-[benzyl-(4-chloro-2-fluoro-benzyl)-amino]-2-methyl-phenyl}- methanesulfonamide 19 has been discovered.

Bile acid conjugates of a nonsteroidal glucocorticoid receptor modulator

Bile acid conjugates of a selective nonsteroidal glucocorticoid receptor modulator were prepared and evaluated. Potent GR binding conjugates that showed improved metabolic stability were discovered. However, cellular potency and pharmacokinetics were not substantially improved.