375856-64-7Relevant academic research and scientific papers
Discovery of (R)-1-[2-hydroxy-3-(4-hydroxy-phenyl)-propyl]-4-(4-methyl-benzyl)-piperidin- 4-ol: A novel NR1/2B subtype selective NMDA receptor antagonist
Pinard, Emmanuel,Alanine, Alexander,Bourson, Anne,Buettelmann, Bernd,Gill, Ramanjit,Heitz, Marie-Paule,Jaeschke, Georg,Mutel, Vincent,Trube, Gerhard,Wyler, Rene
, p. 2173 - 2176 (2007/10/03)
Starting from Ro-25-6981 as a lead compound, highly potent and selective NR1/2B subtype selective NMDA receptor antagonists, with low activity at α1 adrenergic receptors were developed.
