37597-30-1

Upstream product

• 552-20-5 epitruxillic acid 
• 10026-13-8 phosphorus pentachloride 
• 490-19-7 γ-truxillic acid 
• 140-10-3 (E)-3-phenylacrylic acid 
• 51978-94-0 (E)-3-methyl-4-nitro-5-styrylisoxazole 
• 65037-39-0 trans-1,3-di-(3-methyl-4-nitroisoxazol-5-yl)-trans-2,cis-4-diphenylcyclobutane 
• 490-20-0 truxillic acid 

Downstream Products

• 37520-13-1 1,1'-(2,4-diphenyl-cyclobutane-1,3-dicarbonyl)-bis-piperidine 
• 38779-42-9 2c,4t-diphenyl-cyclobutane-1r,3t-diyldiamine 
• 102759-91-1 N,N'-(2c,4t-diphenyl-cyclobutane-1r,3t-diyl)-bis-carbamic acid ethyl ester 
• 106709-79-9 2c,4t-diphenyl-cyclobutane-1r,3t-dicarboxylic acid diamide 
• 108039-40-3 optically inactive 1r,3t-bis-((4ar,4bt,9at,14at)-dodecahydro-tripyrido[1,2-a;1',2'-c;3'',2''-e]pyrimidine-1-carbonyl)-2c,4t-diphenyl-cyclobutane 
• 490-17-5 2,4-diphenyl-cyclobutane-1,3-dicarboxylic acid bis-(2-methoxycarbonyl-tropan-3-yl ester) 
• 37518-23-3 4,4'-(2,4-diphenyl-cyclobutane-1,3-dicarbonyl)-bis-morpholine 
• 106708-15-0 2,4-Diphenyl-cyclobutane-1,3-dicarboxylic acid bis-[(4-diethylamino-butyl)-amide]; hydrochloride 
• 104839-81-8 2,4-Diphenyl-cyclobutane-1,3-dicarboxylic acid bis-[(4-diethylamino-butyl)-amide] 
• 104839-80-7 2,4-Diphenyl-cyclobutane-1,3-dicarboxylic acid bis-[(3-pyrrolidin-1-yl-propyl)-amide] 
• 106709-74-4 α-truxillic acid bis<(4-piperidylbutyl)amide> 
• 106709-75-5 2,4-Diphenyl-cyclobutane-1,3-dicarboxylic acid bis-[(2-diethylamino-ethyl)-amide]; hydrochloride 
• 104854-53-7 2,4-Diphenyl-cyclobutane-1,3-dicarboxylic acid bis-[(2-diethylamino-ethyl)-amide] 

Relevant academic research and scientific papers

The Antinociceptive Agent SBFI-26 Binds to Anandamide Transporters FABP5 and FABP7 at Two Different Sites

Human FABP5 and FABP7 are intracellular endocannabinoid transporters. SBFI-26 is an α-truxillic acid 1-naphthyl monoester that competitively inhibits the activities of FABP5 and FABP7 and produces antinociceptive and anti-inflammatory effects in mice. The

Structure-antinociceptive activity studies of incarvillateine, a monoterpene alkaloid from Incarvillea sinensis

Incarvillateine (1), a new monoterpene alkaloid carrying a characteristic cyclobutane ring, has been found to show significant antinociceptive activity in a formalin-induced pain model in mice. To investigate the correlation between its structure and anti

SAR studies on truxillic acid mono esters as a new class of antinociceptive agents targeting fatty acid binding proteins

Fatty acid binding proteins (FABPs) serve as critical modulators of endocannabinoid signaling by facilitating the intracellular transport of anandamide and whose inhibition potentiates anandamide signaling. Our previous work has identified a novel small-m

α-TRUXILLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF

The present invention provides a compound, and method of inhibiting the activity of a Fatty Acid Binding Protein (FABP) comprising contacting the FABP with a compound, said compound having the structure : Formula (I)

Unambiguous Proof of Nitrile Formation from Pyrazine Skeleton through Photo-Oxidative Degradation. Isolation and Structural Determination of Photodegraded Product of Amorphous Poly(2,5-distyrylpyrazine)

In the presence of oxygen, amorphous poly(2,5-distyrylpyrazine) film was readily photodegraded, accompanied by cleavage of the pyrazine rings in the main chain.From the photodegraded film, t-2,c-4-diphenylcyclobutane-r-1,t-3-dicarbonitrile was isolated in

PREPARATION OF CHLORO-α-TRUXILLIC ACIDS VIA 3-METHYL-4-NITRO-5-STYRYLISOXAZOLE PHOTODIMERS

Chloro-α-truxillic acids (3b-e) were prepared by oxidation of the photodimers (2b-e) of 3-methyl-4-nitro-5-chlorostyrylisoxazoles (1b-e).